Familial and socioeconomic contributions to premorbid functioning in psychosis: Impact on age at onset and treatment response

Familial and socioeconomic contributions to premorbid functioning in psychosis: Impact on age at onset and treatment response

AbstractBackground.Premorbid adjustment (PA) abnormalities in psychotic disorders are associated with an earlier age at onset (AAO) and unfavorable clinical outcomes, including treatment resistance. Prior family studies suggest that familial liability, likely reflecting increased genetic risk, and s...

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Main Authors: Alex Hatzimanolis, Pentagiotissa Stefanatou, Emmanouil Kattoulas, Irene Ralli, Stefanos Dimitrakopoulos, Stefania Foteli, Ioannis Kosteletos, Leonidas Mantonakis, Mirjana Selakovic, Rigas-Filippos Soldatos, Ilias Vlachos, Lida-Alkisti Xenaki, Nikolaos Smyrnis, Nicholas C. Stefanis
Format: Article
Language:English
Published: Cambridge University Press 2020-01-01
Series:European Psychiatry
Subjects:
Family history
first-episode psychosis
premorbid adjustment
schizophrenia
socioeconomic status
treatment response
Online Access:https://www.cambridge.org/core/product/identifier/S0924933820000413/type/journal_article

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