More than a marker: potential pathogenic functions of MAP2
Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic marker. It influences microtubule dynamics and microtubule/actin interactions to control neurite outgrowth and synaptic funct...
Main Authors: | Rebecca A. DeGiosio, Melanie J. Grubisha, Matthew L. MacDonald, Brandon C. McKinney, Carlos J. Camacho, Robert A. Sweet |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
|
Series: | Frontiers in Molecular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2022.974890/full |
Similar Items
-
Investigating Post-translational Modifications in Neuropsychiatric Disease: The Next Frontier in Human Post-mortem Brain Research
by: Melanie J. Grubisha, et al.
Published: (2021-07-01) -
The molecular biology of tubulinopathies: Understanding the impact of variants on tubulin structure and microtubule regulation
by: Katelyn J. Hoff, et al.
Published: (2022-11-01) -
Neuronal Autophagy: Regulations and Implications in Health and Disease
by: Caroline Liénard, et al.
Published: (2024-01-01) -
Gut Microbiota Interaction with the Central Nervous System throughout Life
by: Jorge Ojeda, et al.
Published: (2021-03-01) -
Probenecid Disrupts a Novel Pannexin 1-Collapsin Response Mediator Protein 2 Interaction and Increases Microtubule Stability
by: Xiaoxue Xu, et al.
Published: (2018-05-01)