Evaluation of serum immonogiobulins (A,G,M) and complement components (C3 d) in Isfahan dental clinics patients with recurrent aphlus stomatitis
Recurrent aphtus stomatitis (RAS) is an oral mucous lesion in patients with no other signs of disease. Investigators have always notified the role of immune system especially humoral immunity in aphtus immunopathogenesis. The aim of this case-controlled study was to measure amount of serum immonogio...
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2000-06-01
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| Series: | Journal of Dental Medicine |
| Subjects: | |
| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4709.pdf&manuscript_id=4709 |
| _version_ | 1819072845403127808 |
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| author | Ghalayani Isfahani P Khorami B |
| author_facet | Ghalayani Isfahani P Khorami B |
| author_sort | Ghalayani Isfahani P |
| collection | DOAJ |
| description | Recurrent aphtus stomatitis (RAS) is an oral mucous lesion in patients with no other signs of disease. Investigators have always notified the role of immune system especially humoral immunity in aphtus immunopathogenesis. The aim of this case-controlled study was to measure amount of serum immonogiobulins (A,G,M) and complement component (C3 d) in patients with RAS and to evaluate any relation between differences in these factors and pathogenesis of RAS. Immonogiobulins (A,G,M) and complement components (C3 Ci) of 50 patients with RAS was measured using single radial immuno diffusion technique. The results were compared with immonogiobulins (A,G,M) and complement components (C3 Cj) of 50 healthy people whom were similar in age and sex with the patients group. Results showed that the patients group had higher level of IgA and IgM while serum lgG was similar in both groups. The C$ was lower in aphtus patients while no significant difference was found in amount of C,|. The sex had no significant effect on serum level of measured factors. From the results it can be concluded that the humoral immunity reaction has an important role in immunopathogenesis of RAS. This humoral response might accurse as a result of cellular immunity reaction. |
| first_indexed | 2024-12-21T17:44:12Z |
| format | Article |
| id | doaj.art-feedc2a912ed4e519a84008bbd0884cb |
| institution | Directory Open Access Journal |
| issn | 1024-641X 2008-2444 |
| language | fas |
| last_indexed | 2024-12-21T17:44:12Z |
| publishDate | 2000-06-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Journal of Dental Medicine |
| spelling | doaj.art-feedc2a912ed4e519a84008bbd0884cb2022-12-21T18:55:33ZfasTehran University of Medical SciencesJournal of Dental Medicine1024-641X2008-24442000-06-01133-47480Evaluation of serum immonogiobulins (A,G,M) and complement components (C3 d) in Isfahan dental clinics patients with recurrent aphlus stomatitisGhalayani Isfahani PKhorami BRecurrent aphtus stomatitis (RAS) is an oral mucous lesion in patients with no other signs of disease. Investigators have always notified the role of immune system especially humoral immunity in aphtus immunopathogenesis. The aim of this case-controlled study was to measure amount of serum immonogiobulins (A,G,M) and complement component (C3 d) in patients with RAS and to evaluate any relation between differences in these factors and pathogenesis of RAS. Immonogiobulins (A,G,M) and complement components (C3 Ci) of 50 patients with RAS was measured using single radial immuno diffusion technique. The results were compared with immonogiobulins (A,G,M) and complement components (C3 Cj) of 50 healthy people whom were similar in age and sex with the patients group. Results showed that the patients group had higher level of IgA and IgM while serum lgG was similar in both groups. The C$ was lower in aphtus patients while no significant difference was found in amount of C,|. The sex had no significant effect on serum level of measured factors. From the results it can be concluded that the humoral immunity reaction has an important role in immunopathogenesis of RAS. This humoral response might accurse as a result of cellular immunity reaction.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4709.pdf&manuscript_id=4709Complement |
| spellingShingle | Ghalayani Isfahani P Khorami B Evaluation of serum immonogiobulins (A,G,M) and complement components (C3 d) in Isfahan dental clinics patients with recurrent aphlus stomatitis Journal of Dental Medicine Complement |
| title | Evaluation of serum immonogiobulins (A,G,M) and complement components (C3 d) in Isfahan dental clinics patients with recurrent aphlus stomatitis |
| title_full | Evaluation of serum immonogiobulins (A,G,M) and complement components (C3 d) in Isfahan dental clinics patients with recurrent aphlus stomatitis |
| title_fullStr | Evaluation of serum immonogiobulins (A,G,M) and complement components (C3 d) in Isfahan dental clinics patients with recurrent aphlus stomatitis |
| title_full_unstemmed | Evaluation of serum immonogiobulins (A,G,M) and complement components (C3 d) in Isfahan dental clinics patients with recurrent aphlus stomatitis |
| title_short | Evaluation of serum immonogiobulins (A,G,M) and complement components (C3 d) in Isfahan dental clinics patients with recurrent aphlus stomatitis |
| title_sort | evaluation of serum immonogiobulins a g m and complement components c3 d in isfahan dental clinics patients with recurrent aphlus stomatitis |
| topic | Complement |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/4709.pdf&manuscript_id=4709 |
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