Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive care
Introduction The direction of the causal link between solid cancers and elevated plasma vitamin B 12 (B 12 ) remains uncertain. Material and methods We retrospectively included patients having two B 12 measurements with a B 12 initially ≥ 1000 ng/l and a solid cancer diagnosed between the measur...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Termedia Publishing House
2021-09-01
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| Series: | Archives of Medical Science |
| Subjects: | |
| Online Access: | https://www.archivesofmedicalscience.com/Evolution-of-plasma-vitamin-B-12-in-patients-with-solid-cancers-during-curative-versus,140974,0,2.html |
| Summary: | Introduction
The direction of the causal link between solid cancers and elevated plasma vitamin B 12 (B 12 ) remains uncertain.
Material and methods
We retrospectively included patients having two B 12 measurements with a B 12 initially ≥ 1000 ng/l and a solid cancer diagnosed between the measurements. Patients were included in the Curative or Supportive group according to their treatments.
Results
B 12 changes over time differed among groups ( p = 0.001): +157.4 ng/L/month in the Supportive care group versus -171.6 ng/L/month in the Curative care group.
Conclusions
The decrease of plasma B 12 in cases of curative care could suggest that this B 12 elevation is secondary to solid cancers. |
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| ISSN: | 1734-1922 1896-9151 |