Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive care
Introduction The direction of the causal link between solid cancers and elevated plasma vitamin B 12 (B 12 ) remains uncertain. Material and methods We retrospectively included patients having two B 12 measurements with a B 12 initially ≥ 1000 ng/l and a solid cancer diagnosed between the measur...
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Format: | Article |
Language: | English |
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Termedia Publishing House
2021-09-01
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Series: | Archives of Medical Science |
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Online Access: | https://www.archivesofmedicalscience.com/Evolution-of-plasma-vitamin-B-12-in-patients-with-solid-cancers-during-curative-versus,140974,0,2.html |
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author | Valentin Lacombe Anne Patsouris Estelle Delattre Carole Lacout Geoffrey Urbanski |
author_facet | Valentin Lacombe Anne Patsouris Estelle Delattre Carole Lacout Geoffrey Urbanski |
author_sort | Valentin Lacombe |
collection | DOAJ |
description | Introduction
The direction of the causal link between solid cancers and elevated plasma vitamin B 12 (B 12 ) remains uncertain.
Material and methods
We retrospectively included patients having two B 12 measurements with a B 12 initially ≥ 1000 ng/l and a solid cancer diagnosed between the measurements. Patients were included in the Curative or Supportive group according to their treatments.
Results
B 12 changes over time differed among groups ( p = 0.001): +157.4 ng/L/month in the Supportive care group versus -171.6 ng/L/month in the Curative care group.
Conclusions
The decrease of plasma B 12 in cases of curative care could suggest that this B 12 elevation is secondary to solid cancers. |
first_indexed | 2024-04-12T16:40:00Z |
format | Article |
id | doaj.art-feeef4ac39b0469dac64771f7dfce7f2 |
institution | Directory Open Access Journal |
issn | 1734-1922 1896-9151 |
language | English |
last_indexed | 2024-04-12T16:40:00Z |
publishDate | 2021-09-01 |
publisher | Termedia Publishing House |
record_format | Article |
series | Archives of Medical Science |
spelling | doaj.art-feeef4ac39b0469dac64771f7dfce7f22022-12-22T03:24:50ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512021-09-011761811181510.5114/aoms/140974140974Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive careValentin Lacombe0Anne Patsouris1Estelle Delattre2Carole Lacout3Geoffrey Urbanski4https://orcid.org/0000-0001-5719-8423Department of Internal Medicine and Clinical Immunology, University Hospital, Angers, FranceMedical Oncology, Ouest Cancerology Institute, Angers, FranceDepartment of Internal Medicine and Clinical Immunology, University Hospital, Angers, FranceDepartment of Internal Medicine and Clinical Immunology, University Hospital, Angers, FranceDepartment of Internal Medicine and Clinical Immunology, University Hospital, Angers, FranceIntroduction The direction of the causal link between solid cancers and elevated plasma vitamin B 12 (B 12 ) remains uncertain. Material and methods We retrospectively included patients having two B 12 measurements with a B 12 initially ≥ 1000 ng/l and a solid cancer diagnosed between the measurements. Patients were included in the Curative or Supportive group according to their treatments. Results B 12 changes over time differed among groups ( p = 0.001): +157.4 ng/L/month in the Supportive care group versus -171.6 ng/L/month in the Curative care group. Conclusions The decrease of plasma B 12 in cases of curative care could suggest that this B 12 elevation is secondary to solid cancers.https://www.archivesofmedicalscience.com/Evolution-of-plasma-vitamin-B-12-in-patients-with-solid-cancers-during-curative-versus,140974,0,2.htmlvitamin b 12neoplasmsneoplasm metastasisantineoplastic agents |
spellingShingle | Valentin Lacombe Anne Patsouris Estelle Delattre Carole Lacout Geoffrey Urbanski Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive care Archives of Medical Science vitamin b 12 neoplasms neoplasm metastasis antineoplastic agents |
title | Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive care |
title_full | Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive care |
title_fullStr | Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive care |
title_full_unstemmed | Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive care |
title_short | Evolution of plasma vitamin B 12 in patients with solid cancers during curative versus supportive care |
title_sort | evolution of plasma vitamin b 12 in patients with solid cancers during curative versus supportive care |
topic | vitamin b 12 neoplasms neoplasm metastasis antineoplastic agents |
url | https://www.archivesofmedicalscience.com/Evolution-of-plasma-vitamin-B-12-in-patients-with-solid-cancers-during-curative-versus,140974,0,2.html |
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