Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance
Background The prognosis of asthmatic outpatients with COVID-19 needs to be clarified. The objectives of this study were: 1) to investigate the characteristics and outcomes of asthmatic patients receiving initial ambulatory care and home monitoring for COVID-19 with Covidom, a telesurveillance solut...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2022-10-01
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| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/8/4/00012-2022.full |
| _version_ | 1827931481996001280 |
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| author | Antoine Beurnier Youri Yordanov Agnès Dechartres Aurélien Dinh Erwan Debuc François-Xavier Lescure Patrick Jourdain Luc Jaulmes Marc Humbert |
| author_facet | Antoine Beurnier Youri Yordanov Agnès Dechartres Aurélien Dinh Erwan Debuc François-Xavier Lescure Patrick Jourdain Luc Jaulmes Marc Humbert |
| author_sort | Antoine Beurnier |
| collection | DOAJ |
| description | Background
The prognosis of asthmatic outpatients with COVID-19 needs to be clarified. The objectives of this study were: 1) to investigate the characteristics and outcomes of asthmatic patients receiving initial ambulatory care and home monitoring for COVID-19 with Covidom, a telesurveillance solution; and 2) to compare the characteristics and outcomes between asthmatic and non-asthmatic patients.
Methods
Inclusion criteria were age ≥18 years, suspected or confirmed COVID-19 diagnosis allowing initial ambulatory care, registration in Covidom between March 2020 and April 2021 and completion of the initial medical questionnaire. We compared clinical characteristics and outcomes between asthmatic and non-asthmatic patients, and we evaluated whether asthma was independently associated with clinical worsening (hospitalisation or death) within 30 days follow-up using a multivariate logistic regression model.
Results
33 815 patients met the inclusion criteria. Asthma was reported in 4276 (12.6%). The main comorbidities among asthmatic patients were obesity (23.1%), hypertension (12.7%) and diabetes (4.5%). As compared with non-asthmatic patients, asthmatic patients were more often female (70.0 versus 62.1%, p<0.001), of younger age (42.2 versus 43.8 years, p<0.001) and obese (23.1 versus 17.6%, p<0.001). The rate of hospitalisation did not differ significantly (4.7 versus 4.2%, p=0.203) and no asthmatic patient died during follow-up (versus 25 non-asthmatic patients, 0.1%; p=0.109). In multivariate analysis, asthma was independently associated with higher risk of clinical worsening (OR 1.23, 95% CI 1.04–1.44, p=0.013).
Conclusion
In a large French cohort of patients receiving initial ambulatory care and home monitoring for COVID-19, asthma was independently associated with higher risk of clinical worsening although no asthmatic patient died within the 30 days follow-up. |
| first_indexed | 2024-03-13T06:53:20Z |
| format | Article |
| id | doaj.art-fef494e0aeab4538aa16e962d690f63c |
| institution | Directory Open Access Journal |
| issn | 2312-0541 |
| language | English |
| last_indexed | 2024-03-13T06:53:20Z |
| publishDate | 2022-10-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | ERJ Open Research |
| spelling | doaj.art-fef494e0aeab4538aa16e962d690f63c2023-06-07T13:30:36ZengEuropean Respiratory SocietyERJ Open Research2312-05412022-10-018410.1183/23120541.00012-202200012-2022Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillanceAntoine Beurnier0Youri Yordanov1Agnès Dechartres2Aurélien Dinh3Erwan Debuc4François-Xavier Lescure5Patrick Jourdain6Luc Jaulmes7Marc Humbert8 Université Paris-Saclay, Faculty of Medicine, INSERM UMR_S 999, Service de physiologie et d'explorations fonctionnelles respiratoires, CRISALIS/F-CRIN Network, Hôpital Bicêtre, Le Kremlin-Bicêtre, France Sorbonne Université, Assistance Publique-Hopitaux de Paris (AP-HP), Hôpital Saint Antoine, Service d'Accueil des Urgences, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, UMR-S 1136, Paris, France Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, UMR-S 1136, AP-HP.Sorbonne Université, Hopital Pitié Salpêtrière, Département de Santé Publique, Centre de Pharmaco-épidémiologie de l'AP-HP (Cephepi), Paris, France Infectious Disease Department, R. Poincaré University Hospital, Garches, AP-HP, Paris Saclay University, Paris, France AP-HP, Paris, France Department of Infectious and Tropical Diseases, AP-HP, Bichat-Claude Bernard University Hospital, Paris, France DMU COREVE, GHU Paris Saclay, AP-HP, Paris, France AP-HP.Sorbonne Université, Hopital Pitié Salpêtrière, Département de Santé Publique, Centre de Pharmaco-épidémiologie de l'AP-HP (Cephepi), Paris, France Université Paris-Saclay, Faculty of Medicine, INSERM UMR_S 999, AP-HP, Service de pneumologie et soins intensifs respiratoires, CRISALIS/F-CRIN network, Hôpital Bicêtre, Le Kremlin-Bicêtre, France Background The prognosis of asthmatic outpatients with COVID-19 needs to be clarified. The objectives of this study were: 1) to investigate the characteristics and outcomes of asthmatic patients receiving initial ambulatory care and home monitoring for COVID-19 with Covidom, a telesurveillance solution; and 2) to compare the characteristics and outcomes between asthmatic and non-asthmatic patients. Methods Inclusion criteria were age ≥18 years, suspected or confirmed COVID-19 diagnosis allowing initial ambulatory care, registration in Covidom between March 2020 and April 2021 and completion of the initial medical questionnaire. We compared clinical characteristics and outcomes between asthmatic and non-asthmatic patients, and we evaluated whether asthma was independently associated with clinical worsening (hospitalisation or death) within 30 days follow-up using a multivariate logistic regression model. Results 33 815 patients met the inclusion criteria. Asthma was reported in 4276 (12.6%). The main comorbidities among asthmatic patients were obesity (23.1%), hypertension (12.7%) and diabetes (4.5%). As compared with non-asthmatic patients, asthmatic patients were more often female (70.0 versus 62.1%, p<0.001), of younger age (42.2 versus 43.8 years, p<0.001) and obese (23.1 versus 17.6%, p<0.001). The rate of hospitalisation did not differ significantly (4.7 versus 4.2%, p=0.203) and no asthmatic patient died during follow-up (versus 25 non-asthmatic patients, 0.1%; p=0.109). In multivariate analysis, asthma was independently associated with higher risk of clinical worsening (OR 1.23, 95% CI 1.04–1.44, p=0.013). Conclusion In a large French cohort of patients receiving initial ambulatory care and home monitoring for COVID-19, asthma was independently associated with higher risk of clinical worsening although no asthmatic patient died within the 30 days follow-up.http://openres.ersjournals.com/content/8/4/00012-2022.full |
| spellingShingle | Antoine Beurnier Youri Yordanov Agnès Dechartres Aurélien Dinh Erwan Debuc François-Xavier Lescure Patrick Jourdain Luc Jaulmes Marc Humbert Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance ERJ Open Research |
| title | Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance |
| title_full | Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance |
| title_fullStr | Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance |
| title_full_unstemmed | Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance |
| title_short | Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance |
| title_sort | characteristics and outcomes of asthmatic outpatients with covid 19 who receive home telesurveillance |
| url | http://openres.ersjournals.com/content/8/4/00012-2022.full |
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