Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis

Anne Huhtala,1 Juhani Pietilä,1,2 Petri Mäkinen,1,2 Hannu Uusitalo1–3 1Silmäasema Eye Hospital, 2SILK, Department of Ophthalmology, School of Medicine, University of Tampere, 3TAUH Eye Center, Tampere University Hospital, Tampere, Finland Purpose: The aim of th...

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Main Authors: Huhtala A, Pietilä J, Mäkinen P, Uusitalo H
Format: Article
Language:English
Published: Dove Medical Press 2016-03-01
Series:Clinical Ophthalmology
Subjects:
Online Access:https://www.dovepress.com/femtosecond-lasers-for-laser-in-situ-keratomileusis-a-systematic-revie-peer-reviewed-article-OPTH
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author Huhtala A
Pietilä J
Mäkinen P
Uusitalo H
author_facet Huhtala A
Pietilä J
Mäkinen P
Uusitalo H
author_sort Huhtala A
collection DOAJ
description Anne Huhtala,1 Juhani Pietilä,1,2 Petri Mäkinen,1,2 Hannu Uusitalo1–3 1Silmäasema Eye Hospital, 2SILK, Department of Ophthalmology, School of Medicine, University of Tampere, 3TAUH Eye Center, Tampere University Hospital, Tampere, Finland Purpose: The aim of this study was to review and meta-analyze whether there are differences between reported femtosecond (FS) lasers for laser-assisted in situ keratomileusis (LASIK) in terms of efficacy, predictability, and safety as primary outcomes and corneal flap thickness measurements and pre- and postoperative complications as secondary outcomes.Methods: A comprehensive literature search of PubMed, Science Direct, Scopus, and Cochrane CENTRAL Trials Library databases was conducted to identify the relevant prospective randomized controlled trials of FS lasers for LASIK. Thirty-one articles describing a total of 5,404 eyes were included.Results: Based on efficacy, IntraLase FS 10 and 30 kHz gave the best results. Based on predictability and safety, there were no differences between various FS lasers. FEMTO LDV and IntraLase FS 60 kHz produced the most accurate flap thicknesses. IntraLase and Wavelight SF200 had the fewest intraoperative complications. IntraLase, Visumax, and Wavelight FS200 had the most seldom postoperative complications.Conclusion: There were dissimilarities between different FS lasers based on efficacy and intraoperative and postoperative complications. All FS lasers were predictable and safe for making corneal flaps in LASIK. Keywords: femtosecond laser, laser in situ keratomileusis, LASIK, meta-analysis
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spelling doaj.art-fefaec0f708d4ca5ba6cf8821695b8eb2022-12-21T23:10:55ZengDove Medical PressClinical Ophthalmology1177-54832016-03-012016Issue 139340425861Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysisHuhtala APietilä JMäkinen PUusitalo HAnne Huhtala,1 Juhani Pietilä,1,2 Petri Mäkinen,1,2 Hannu Uusitalo1–3 1Silmäasema Eye Hospital, 2SILK, Department of Ophthalmology, School of Medicine, University of Tampere, 3TAUH Eye Center, Tampere University Hospital, Tampere, Finland Purpose: The aim of this study was to review and meta-analyze whether there are differences between reported femtosecond (FS) lasers for laser-assisted in situ keratomileusis (LASIK) in terms of efficacy, predictability, and safety as primary outcomes and corneal flap thickness measurements and pre- and postoperative complications as secondary outcomes.Methods: A comprehensive literature search of PubMed, Science Direct, Scopus, and Cochrane CENTRAL Trials Library databases was conducted to identify the relevant prospective randomized controlled trials of FS lasers for LASIK. Thirty-one articles describing a total of 5,404 eyes were included.Results: Based on efficacy, IntraLase FS 10 and 30 kHz gave the best results. Based on predictability and safety, there were no differences between various FS lasers. FEMTO LDV and IntraLase FS 60 kHz produced the most accurate flap thicknesses. IntraLase and Wavelight SF200 had the fewest intraoperative complications. IntraLase, Visumax, and Wavelight FS200 had the most seldom postoperative complications.Conclusion: There were dissimilarities between different FS lasers based on efficacy and intraoperative and postoperative complications. All FS lasers were predictable and safe for making corneal flaps in LASIK. Keywords: femtosecond laser, laser in situ keratomileusis, LASIK, meta-analysishttps://www.dovepress.com/femtosecond-lasers-for-laser-in-situ-keratomileusis-a-systematic-revie-peer-reviewed-article-OPTHFemtosecond laserlaser in situ keratomileusisLASIK
spellingShingle Huhtala A
Pietilä J
Mäkinen P
Uusitalo H
Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
Clinical Ophthalmology
Femtosecond laser
laser in situ keratomileusis
LASIK
title Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_full Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_fullStr Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_full_unstemmed Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_short Femtosecond lasers for laser in situ keratomileusis: a systematic review and meta-analysis
title_sort femtosecond lasers for laser in situ keratomileusis a systematic review and meta analysis
topic Femtosecond laser
laser in situ keratomileusis
LASIK
url https://www.dovepress.com/femtosecond-lasers-for-laser-in-situ-keratomileusis-a-systematic-revie-peer-reviewed-article-OPTH
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AT pietilaj femtosecondlasersforlaserinsitukeratomileusisasystematicreviewandmetaanalysis
AT makinenp femtosecondlasersforlaserinsitukeratomileusisasystematicreviewandmetaanalysis
AT uusitaloh femtosecondlasersforlaserinsitukeratomileusisasystematicreviewandmetaanalysis