Comb Atrophy after Bile Duct Ligation in Chickens
Gross, histological, and immunohistochemical changes in the combs of chickens after bile duct ligation (BDL) are described. Gross reductions in comb size and volume and lower serum testosterone levels were evident in chickens after BDL. Histologically, atrophic combs were characterized by reduced bl...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Japan Poultry Science Association
2018-01-01
|
| Series: | The Journal of Poultry Science |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/55/1/55_0170053/_html/-char/en |
| _version_ | 1797817048551653376 |
|---|---|
| author | Kazuki Yoshioka Shiho Imai Hiromi Ikadai Jun Nagasao Masashi Tsujio |
| author_facet | Kazuki Yoshioka Shiho Imai Hiromi Ikadai Jun Nagasao Masashi Tsujio |
| author_sort | Kazuki Yoshioka |
| collection | DOAJ |
| description | Gross, histological, and immunohistochemical changes in the combs of chickens after bile duct ligation (BDL) are described. Gross reductions in comb size and volume and lower serum testosterone levels were evident in chickens after BDL. Histologically, atrophic combs were characterized by reduced blood capillary diameter, decreased acid mucopolysaccharides, thinning of the stratum germinativum of the epidermis and dermis, and reduced immunostaining intensity of androgen receptors. These results suggest that the affected cells in atrophic combs are androgen targets. BDL caused testicular atrophy in chickens, a primary complication of liver disease, and the resultant low serum testosterone levels subsequently caused atrophy of the comb. In other words, the atrophy of the comb observed in BDL chickens was a secondary complication of liver dysfunction that simulated the effects of liver disease. |
| first_indexed | 2024-03-13T08:46:39Z |
| format | Article |
| id | doaj.art-fefc15a87fda47b6a02aaa285ed73d88 |
| institution | Directory Open Access Journal |
| issn | 1346-7395 1349-0486 |
| language | English |
| last_indexed | 2024-03-13T08:46:39Z |
| publishDate | 2018-01-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj.art-fefc15a87fda47b6a02aaa285ed73d882023-05-30T02:04:14ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862018-01-01551656910.2141/jpsa.0170053jpsaComb Atrophy after Bile Duct Ligation in ChickensKazuki Yoshioka0Shiho Imai1Hiromi Ikadai2Jun Nagasao3Masashi Tsujio4Laboratory of Veterinary Anatomy, School of Veterinary Medicine, Kitasato UniversityLaboratory of Veterinary Anatomy, School of Veterinary Medicine, Kitasato UniversityLaboratory of Veterinary Parasitology, School of Veterinary Medicine, Kitasato UniversityHonma Pet ClinicDepartment of Veterinary Anatomy, Joint Faculty of Veterinary Medicine, Kagoshima UniversityGross, histological, and immunohistochemical changes in the combs of chickens after bile duct ligation (BDL) are described. Gross reductions in comb size and volume and lower serum testosterone levels were evident in chickens after BDL. Histologically, atrophic combs were characterized by reduced blood capillary diameter, decreased acid mucopolysaccharides, thinning of the stratum germinativum of the epidermis and dermis, and reduced immunostaining intensity of androgen receptors. These results suggest that the affected cells in atrophic combs are androgen targets. BDL caused testicular atrophy in chickens, a primary complication of liver disease, and the resultant low serum testosterone levels subsequently caused atrophy of the comb. In other words, the atrophy of the comb observed in BDL chickens was a secondary complication of liver dysfunction that simulated the effects of liver disease.https://www.jstage.jst.go.jp/article/jpsa/55/1/55_0170053/_html/-char/enandrogen receptoratrophybile duct ligationcomb |
| spellingShingle | Kazuki Yoshioka Shiho Imai Hiromi Ikadai Jun Nagasao Masashi Tsujio Comb Atrophy after Bile Duct Ligation in Chickens The Journal of Poultry Science androgen receptor atrophy bile duct ligation comb |
| title | Comb Atrophy after Bile Duct Ligation in Chickens |
| title_full | Comb Atrophy after Bile Duct Ligation in Chickens |
| title_fullStr | Comb Atrophy after Bile Duct Ligation in Chickens |
| title_full_unstemmed | Comb Atrophy after Bile Duct Ligation in Chickens |
| title_short | Comb Atrophy after Bile Duct Ligation in Chickens |
| title_sort | comb atrophy after bile duct ligation in chickens |
| topic | androgen receptor atrophy bile duct ligation comb |
| url | https://www.jstage.jst.go.jp/article/jpsa/55/1/55_0170053/_html/-char/en |
| work_keys_str_mv | AT kazukiyoshioka combatrophyafterbileductligationinchickens AT shihoimai combatrophyafterbileductligationinchickens AT hiromiikadai combatrophyafterbileductligationinchickens AT junnagasao combatrophyafterbileductligationinchickens AT masashitsujio combatrophyafterbileductligationinchickens |