The first case of Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case report
Objective: Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is a rare autoimmune and paraneoplastic encephalitis caused by the N-methyl-d-aspartate receptor antibody which is related to tumors, such as teratomas of the ovaries. To our knowledge, this is the first reported case of Anti-NM...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-07-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455919301263 |
| _version_ | 1818496420266639360 |
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| author | Eun Hye Cho Jung Mi Byun Ha Young Park Mi Ri Kang Yoon Jung Jung Chul Hoi Jeong Young Nam Kim Kyung Bok Lee Moon Su Sung Dae Hoon Jeong |
| author_facet | Eun Hye Cho Jung Mi Byun Ha Young Park Mi Ri Kang Yoon Jung Jung Chul Hoi Jeong Young Nam Kim Kyung Bok Lee Moon Su Sung Dae Hoon Jeong |
| author_sort | Eun Hye Cho |
| collection | DOAJ |
| description | Objective: Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is a rare autoimmune and paraneoplastic encephalitis caused by the N-methyl-d-aspartate receptor antibody which is related to tumors, such as teratomas of the ovaries. To our knowledge, this is the first reported case of Anti-NMDAR encephalitis associated with ovarian mucinous cystadenoma. Case report: A 23-year-old woman with a flu-like illness, confused mental status, and behavioral changes presented to the hospital. A right-sided ovarian tumor was detected during the work-up and was suspected to be a teratoma that might have caused the encephalitis. A laparoscopic right salpingo-oophorectomy (RSO) was performed. Histopathological examination revealed a mucinous cystadenoma. She recovered gradually and had complete resolution of symptoms after surgical removal of the mucinous cystadenoma and immunotherapy. Conclusion: Even though anti-NMDAR encephalitis is caused by ovarian teratoma because it contains various types of tissues, ovarian tumors in anti-NMDAR encephalitis may not be limited to ovarian teratomas. Keywords: Anti-NMDAR encephalitis, Ovarian tumor, Mucinous cystadenoma |
| first_indexed | 2024-12-10T18:33:09Z |
| format | Article |
| id | doaj.art-fefccb774c9847bab0b36840df036220 |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-10T18:33:09Z |
| publishDate | 2019-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-fefccb774c9847bab0b36840df0362202022-12-22T01:37:54ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592019-07-01584557559The first case of Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case reportEun Hye Cho0Jung Mi Byun1Ha Young Park2Mi Ri Kang3Yoon Jung Jung4Chul Hoi Jeong5Young Nam Kim6Kyung Bok Lee7Moon Su Sung8Dae Hoon Jeong9Department of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, South KoreaDepartment of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, South Korea; Paik Institute for Clinical Research, Inje University, College of Medicine, South Korea; Corresponding author. Department of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, 75 Bokji-ro, Busanjin-gu, Busan, 473920, South Korea. Fax: +82 51 897 6380.Department of Pathology, Busan Paik Hospital, Inje University, College of Medicine, South KoreaDepartment of Neurology, Busan Paik Hospital, Inje University, College of Medicine, South KoreaDepartment of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, South KoreaDepartment of Obstetrics and Gynecology, Haeundae Paik Hospital, Inje University, College of Medicine, South KoreaDepartment of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, South Korea; Paik Institute for Clinical Research, Inje University, College of Medicine, South KoreaDepartment of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, South Korea; Paik Institute for Clinical Research, Inje University, College of Medicine, South KoreaDepartment of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, South Korea; Paik Institute for Clinical Research, Inje University, College of Medicine, South KoreaDepartment of Obstetrics and Gynecology, Busan Paik Hospital, Inje University, College of Medicine, South Korea; Paik Institute for Clinical Research, Inje University, College of Medicine, South KoreaObjective: Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is a rare autoimmune and paraneoplastic encephalitis caused by the N-methyl-d-aspartate receptor antibody which is related to tumors, such as teratomas of the ovaries. To our knowledge, this is the first reported case of Anti-NMDAR encephalitis associated with ovarian mucinous cystadenoma. Case report: A 23-year-old woman with a flu-like illness, confused mental status, and behavioral changes presented to the hospital. A right-sided ovarian tumor was detected during the work-up and was suspected to be a teratoma that might have caused the encephalitis. A laparoscopic right salpingo-oophorectomy (RSO) was performed. Histopathological examination revealed a mucinous cystadenoma. She recovered gradually and had complete resolution of symptoms after surgical removal of the mucinous cystadenoma and immunotherapy. Conclusion: Even though anti-NMDAR encephalitis is caused by ovarian teratoma because it contains various types of tissues, ovarian tumors in anti-NMDAR encephalitis may not be limited to ovarian teratomas. Keywords: Anti-NMDAR encephalitis, Ovarian tumor, Mucinous cystadenomahttp://www.sciencedirect.com/science/article/pii/S1028455919301263 |
| spellingShingle | Eun Hye Cho Jung Mi Byun Ha Young Park Mi Ri Kang Yoon Jung Jung Chul Hoi Jeong Young Nam Kim Kyung Bok Lee Moon Su Sung Dae Hoon Jeong The first case of Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case report Taiwanese Journal of Obstetrics & Gynecology |
| title | The first case of Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case report |
| title_full | The first case of Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case report |
| title_fullStr | The first case of Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case report |
| title_full_unstemmed | The first case of Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case report |
| title_short | The first case of Anti-N-methyl-d-aspartate receptor encephalitis (Anti-NMDAR encephalitis) associated with ovarian mucinous cystadenoma: A case report |
| title_sort | first case of anti n methyl d aspartate receptor encephalitis anti nmdar encephalitis associated with ovarian mucinous cystadenoma a case report |
| url | http://www.sciencedirect.com/science/article/pii/S1028455919301263 |
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