Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3′-diiodo-L-thyronine (3,3′-T2) in Human Serum: A Feasibility Study

Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3′-diiodo-L-thyronine (3,3′-T2) in Human Serum: A Feasibility Study

3,5-diiodo-L-thyronine (3,5-T2) is an endogenous derivative of thyroid hormone with potential metabolic effects. It has been detected in human blood by immunological methods, but a reliable assay based on mass spectrometry (MS), which is now regarded as the gold standard in clinical chemistry, is no...

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Bibliographic Details
Main Authors: Leonardo Lorenzini, Nhat Minh Nguyen, Ginevra Sacripanti, Enrico Serni, Marco Borsò, Federica Saponaro, Elena Cecchi, Tommaso Simoncini, Sandra Ghelardoni, Riccardo Zucchi, Alessandro Saba
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Endocrinology
Subjects:
thyroid hormones
thyroid hormones metabolites
3, 5-diiodo-L-thyronine
mass spectrometry
T2
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00088/full

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