Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification

Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification

Acquired drug resistance constitutes a serious obstacle to the successful therapy of cancer. In the process of therapy resistance, microRNAs can play important roles. In order to combat resistance formation and to improve the efficacy of chemotherapeutics, the mechanisms of the multifaceted hsa-miR-...

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Bibliographic Details
Main Authors: Bianca Köhler, Sviatlana Dubovik, Elisa Hörterer, Ulrich Wilk, Jan Bernd Stöckl, Hande Tekarslan-Sahin, Bojan Ljepoja, Philipp Paulitschke, Thomas Fröhlich, Ernst Wagner, Andreas Roidl
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
cancer
glutathione S-transferase
miR-200c
chemotherapy
resistance
Online Access:https://www.mdpi.com/2072-6694/14/22/5554

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