Effect observation of human fibrin sealant in the surgery of pterygium
AIM: To compare the efficacy and characteristic of human fibrin sealant in the surgery of pterygium. <p>METHODS: A prospective randomized controlled study was conducted. A total of 148 eyes of 148 patients with pterygium were involved in the study from June 2016 to September 2017. All patients...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2018-09-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://ies.ijo.cn/cn_publish/2018/9/201809043.pdf |
| _version_ | 1817981342673010688 |
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| author | Hong-Yan Sun Jiang Zhu |
| author_facet | Hong-Yan Sun Jiang Zhu |
| author_sort | Hong-Yan Sun |
| collection | DOAJ |
| description | AIM: To compare the efficacy and characteristic of human fibrin sealant in the surgery of pterygium. <p>METHODS: A prospective randomized controlled study was conducted. A total of 148 eyes of 148 patients with pterygium were involved in the study from June 2016 to September 2017. All patients were divided into two groups receiving 10-0 vicryl sutures or human fibrin sealant respectively. Patients were seen on postoperative 1, 3d, 1wk, 1, 3, and 6mo after surgery. The duration of surgery, level of patient discomfort, pterygium recurrence, and complications were retrospectively analyzed between two groups. <p>RESULTS: The duration of surgery in observer group was 15.23±2.26min and 28.22±2.70min in control group, the difference was statistically significant(<i>t</i>=-31.75, <i>P</i><0.01). One week later, the level of patient discomfort at 1, 3 and 7d after surgery were 0.62±0.69, 0.34±0.50, 0.16±0.37 in observation group, and the level of patient discomfort were 1.15±0.92, 0.54±0.60, 0.18±0.38 in control group, and the difference were statistically significant in observer group and control group(<i>P</i><0.01); comparison between any two means in either group was significantly different(<i>P</i><0.01). There were significant difference between the two groups on postoperative 1, 3d after surgery(<i>t</i>=-3.94, -2.22; <i>P</i><0.05), and there was not significant difference between the two groups on postoperative 7d after surgery(<i>t</i>=-0.22, <i>P</i>>0.05). Two eyes(2.7%)were recurrent on postoperative 6mo after surgery in observation group and 4 of 74 eyes(5.4%)in control group, demonstrated no significant differences(<i>χ</i><sup>2</sup>=24.2, <i>P</i>>0.05). Five of 74 eyes(6.8%)were with complications in observation group and 6 of 74 eyes(8.1%)in control group, demonstrated no significant differences(<i>χ</i><sup>2</sup>=16.32, <i>P</i>>0.05). <p>CONCLUSION: The duration of surgery, patient discomfort level were reduced markedly, as less flap dislocation and postoperative reaction with human fibrin sealant compared with 10-0 vicryl sutures. A good result can be obtained by using the human fibrin sealant in the surgery of pterygium. |
| first_indexed | 2024-04-13T23:04:40Z |
| format | Article |
| id | doaj.art-ff0008ba51f041f2b5762814cba2364e |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-04-13T23:04:40Z |
| publishDate | 2018-09-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-ff0008ba51f041f2b5762814cba2364e2022-12-22T02:25:43ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232018-09-011891735173810.3980/j.issn.1672-5123.2018.9.43Effect observation of human fibrin sealant in the surgery of pterygiumHong-Yan Sun0Jiang Zhu1Department of Ophthalmology,Suqian First Hospital, Suqian 223800, Jiangsu Province, ChinaDepartment of Ophthalmology,Suqian First Hospital, Suqian 223800, Jiangsu Province, ChinaAIM: To compare the efficacy and characteristic of human fibrin sealant in the surgery of pterygium. <p>METHODS: A prospective randomized controlled study was conducted. A total of 148 eyes of 148 patients with pterygium were involved in the study from June 2016 to September 2017. All patients were divided into two groups receiving 10-0 vicryl sutures or human fibrin sealant respectively. Patients were seen on postoperative 1, 3d, 1wk, 1, 3, and 6mo after surgery. The duration of surgery, level of patient discomfort, pterygium recurrence, and complications were retrospectively analyzed between two groups. <p>RESULTS: The duration of surgery in observer group was 15.23±2.26min and 28.22±2.70min in control group, the difference was statistically significant(<i>t</i>=-31.75, <i>P</i><0.01). One week later, the level of patient discomfort at 1, 3 and 7d after surgery were 0.62±0.69, 0.34±0.50, 0.16±0.37 in observation group, and the level of patient discomfort were 1.15±0.92, 0.54±0.60, 0.18±0.38 in control group, and the difference were statistically significant in observer group and control group(<i>P</i><0.01); comparison between any two means in either group was significantly different(<i>P</i><0.01). There were significant difference between the two groups on postoperative 1, 3d after surgery(<i>t</i>=-3.94, -2.22; <i>P</i><0.05), and there was not significant difference between the two groups on postoperative 7d after surgery(<i>t</i>=-0.22, <i>P</i>>0.05). Two eyes(2.7%)were recurrent on postoperative 6mo after surgery in observation group and 4 of 74 eyes(5.4%)in control group, demonstrated no significant differences(<i>χ</i><sup>2</sup>=24.2, <i>P</i>>0.05). Five of 74 eyes(6.8%)were with complications in observation group and 6 of 74 eyes(8.1%)in control group, demonstrated no significant differences(<i>χ</i><sup>2</sup>=16.32, <i>P</i>>0.05). <p>CONCLUSION: The duration of surgery, patient discomfort level were reduced markedly, as less flap dislocation and postoperative reaction with human fibrin sealant compared with 10-0 vicryl sutures. A good result can be obtained by using the human fibrin sealant in the surgery of pterygium.http://ies.ijo.cn/cn_publish/2018/9/201809043.pdfpterygiumhuman fibrin sealantduration of surgerylevel of patient discomfortlevel of patient discomfort |
| spellingShingle | Hong-Yan Sun Jiang Zhu Effect observation of human fibrin sealant in the surgery of pterygium Guoji Yanke Zazhi pterygium human fibrin sealant duration of surgery level of patient discomfort level of patient discomfort |
| title | Effect observation of human fibrin sealant in the surgery of pterygium |
| title_full | Effect observation of human fibrin sealant in the surgery of pterygium |
| title_fullStr | Effect observation of human fibrin sealant in the surgery of pterygium |
| title_full_unstemmed | Effect observation of human fibrin sealant in the surgery of pterygium |
| title_short | Effect observation of human fibrin sealant in the surgery of pterygium |
| title_sort | effect observation of human fibrin sealant in the surgery of pterygium |
| topic | pterygium human fibrin sealant duration of surgery level of patient discomfort level of patient discomfort |
| url | http://ies.ijo.cn/cn_publish/2018/9/201809043.pdf |
| work_keys_str_mv | AT hongyansun effectobservationofhumanfibrinsealantinthesurgeryofpterygium AT jiangzhu effectobservationofhumanfibrinsealantinthesurgeryofpterygium |