Fungistatic Action of N-Acetylcysteine on <i>Candida albicans</i> Biofilms and Its Interaction with Antifungal Agents

Fungistatic Action of N-Acetylcysteine on <i>Candida albicans</i> Biofilms and Its Interaction with Antifungal Agents

Therapies targeted to fungal biofilms, mainly against the matrix, and therapies that do not induce microbial resistance are relevant. N-acetylcysteine (NAC), a mucolytic agent, has shown antimicrobial action. This study evaluated the effect of NAC against fluconazole-susceptible (CaS) and -resistant...

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Bibliographic Details
Main Authors: Thaís Soares Bezerra Santos Nunes, Leticia Matheus Rosa, Yuliana Vega-Chacón, Ewerton Garcia de Oliveira Mima
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Microorganisms
Subjects:
acetylcysteine
biofilms
extracellular matrix
<i>Candida albicans</i>
drug resistance
antifungal agents
Online Access:https://www.mdpi.com/2076-2607/8/7/980

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