Histone ubiquitination-related gene CUL4B promotes lung adenocarcinoma progression and cisplatin resistance

Histone ubiquitination-related gene CUL4B promotes lung adenocarcinoma progression and cisplatin resistance

Background: The role of the histone ubiquitination-related gene in the cisplatin resistance of lung adenocarcinoma (LUAD) remains an intricate subject.Methods: We accessed transcriptome data of both wild type and cisplatin-resistant cells from the GSE108214 dataset, and garnered transcriptome and cl...

Full description

Bibliographic Details
Main Authors:	Yanjun Yin, Lifeng Zhang, Yinchuan Zeng, Diang Chen, Haien Guan, Guoping Ran, Kangming Du
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Series:	Frontiers in Genetics
Subjects:	lung cancer ubiquitination histone CUL4B cisplatin resistance
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2023.1242137/full

Similar Items

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation
by: Sun-Ok Kim, et al.
Published: (2021-07-01)

Importance of Cullin4 Ubiquitin Ligase in Malignant Pleural Mesothelioma
by: Mayura Meerang, et al.
Published: (2020-11-01)

Identification and verification of the prognostic value of CUL7 in colon adenocarcinoma
by: Chengxing Wang, et al.
Published: (2022-10-01)

DNA Damage Response Regulation by Histone Ubiquitination
by: Miyu Sekiguchi, et al.
Published: (2022-07-01)

Ubiquitin Regulation: The Histone Modifying Enzyme′s Story
by: Jianlin Wang, et al.
Published: (2018-08-01)

The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells
by: Shaheen Kabir, et al.
Published: (2019-07-01)

DCAF13 inhibits the p53 signaling pathway by promoting p53 ubiquitination modification in lung adenocarcinoma
by: Shan Wei, et al.
Published: (2024-01-01)

Cul4A Modulates Invasion and Metastasis of Lung Cancer through Regulation of ANXA10
by: Ming-Szu Hung, et al.
Published: (2019-05-01)

Current trends of high-risk gene Cul3 in neurodevelopmental disorders
by: Ping Lin, et al.
Published: (2023-07-01)

Regulation of Histone Ubiquitination in Response to DNA Double Strand Breaks
by: Lanni Aquila, et al.
Published: (2020-07-01)

High Expression of CUL9 Is Prognostic and Predictive for Adjuvant Chemotherapy in High-Risk Stage II and Stage III Colon Cancer
by: Peng Zheng, et al.
Published: (2022-08-01)

Neighborhood from Cul-De-Sac to Gated Community in Turkish Urban Culture: The “Fina”
by: Havva Alkan Bala
Published: (2018-12-01)

Neighborhood from Cul-De-Sac to Gated Community in Turkish Urban Culture: The “Fina”
by: Havva Alkan Bala
Published: (2018-12-01)

High Expressions of CUL4A and TP53 in Colorectal Cancer Predict Poor Survival
by: Chao Li, et al.
Published: (2018-12-01)

CUL4B is a Potential Novel Prognostic Biomarker and is Correlated with Immune Infiltrates in Malignant Pleural Mesothelioma
by: Liu L, et al.
Published: (2022-05-01)

Insights into the diverse mechanisms and effects of variant CUL3-induced familial hyperkalemic hypertension
by: Prashant Sharma, et al.
Published: (2023-10-01)

Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer
by: Lucile M-P Jeusset, et al.
Published: (2019-02-01)

ERN1 dependent regulation of TMED10, MYL9, SPOCK1, CUL4A and CUL4B genes expression at glucose and glutamine deprivations in U87 glioma cells
by: O. H. Minchenko, et al.
Published: (2020-10-01)

Histone Mono-Ubiquitination in Transcriptional Regulation and Its Mark on Life: Emerging Roles in Tissue Development and Disease
by: Liat Oss-Ronen, et al.
Published: (2022-08-01)

Role of the NEDD8 Modification of Cul2 in the Sequential Activation of ECV Complex
by: Roxana I. Sufan, et al.
Published: (2006-11-01)

Integrative analysis illustrates the role of PCDH7 in lung cancer development, cisplatin resistance, and immunotherapy resistance: an underlying target
by: Huakang Li, et al.
Published: (2023-07-01)

Cul4B promotes the progression of ovarian cancer by upregulating the expression of CDK2 and CyclinD1
by: Peng-jing Duan, et al.
Published: (2020-07-01)

Analysis of the Effect of Cul-de-sacs′ Permeability Factors in Low-Rise Residential Areas on Burglary
by: Seungil Kim, et al.
Published: (2017-09-01)

Exo-miR-1290-induced by COX-2 overexpression promotes cancer-associated fibroblasts activation and tumor progression by CUL3-Nrf2 pathway in lung adenocarcinoma
by: Xiaoming Bai, et al.
Published: (2023-09-01)

RETRACTED: CUL4B promotes aggressive phenotypes of HNSCC via the activation of the Wnt/β‐catenin signaling pathway
by: Yuanyuan Wang, et al.
Published: (2019-05-01)

Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions
by: Achim Werner, et al.
Published: (2018-07-01)

Linking Phospho-Gonadotropin Regulated Testicular RNA Helicase (GRTH/DDX25) to Histone Ubiquitination and Acetylation Essential for Spermatid Development During Spermiogenesis
by: Raghuveer Kavarthapu, et al.
Published: (2020-05-01)

MOF negatively regulates estrogen receptor α signaling via CUL4B-mediated protein degradation in breast cancer
by: Xu Zhang, et al.
Published: (2022-09-01)

PRMT5 Selective Inhibitor Enhances Therapeutic Efficacy of Cisplatin in Lung Cancer Cells
by: Khuloud Bajbouj, et al.
Published: (2021-06-01)

Hyperthermia and cisplatin combination therapy promotes caspase-8 accumulation and activation to enhance apoptosis and pyroptosis in cancer cells
by: Guanghui Zi, et al.
Published: (2024-12-01)

Ubiquitin signaling in pancreatic ductal adenocarcinoma
by: Shengnan Lv, et al.
Published: (2023-12-01)

The Role of Epigenetics in Resistance to Cisplatin Chemotherapy in Lung Cancer
by: Steven G. Gray, et al.
Published: (2011-03-01)

Ubiquitination Regulates the Morphogenesis and Function of Sperm Organelles
by: Nobuhiro Nakamura
Published: (2013-12-01)

Sensitization of MCF7 Cells with High Notch1 Activity by Cisplatin and Histone Deacetylase Inhibitors Applied Together
by: Anna Wawruszak, et al.
Published: (2021-05-01)

Role of Epigenetics for the Efficacy of Cisplatin
by: Tatjana Lumpp, et al.
Published: (2024-01-01)

The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis
by: Jie Gao, et al.
Published: (2015-11-01)

Cullin-3 intervenes in muscle atrophy in the elderly by mediating the degradation of nAchRs ubiquitination
by: Jintao Chen, et al.
Published: (2023-11-01)

The deubiquitinase USP8 regulates ovarian cancer cell response to cisplatin by suppressing apoptosis
by: Cristina Corno, et al.
Published: (2022-12-01)

Decoding histone ubiquitylation
by: Jennifer J. Chen, et al.
Published: (2022-08-01)

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage
by: Julianne Kitevski-LeBlanc, et al.
Published: (2017-04-01)