Numb regulates cell tension required for mammary duct elongation

Numb regulates cell tension required for mammary duct elongation

The mammary gland undergoes extensive expansion of a ductal network through the stroma during puberty and is an excellent model for understanding epithelial tube morphogenesis. To investigate a role for Numb, a multifaceted adapter protein, in epithelial tube morphogenesis, we conditionally deleted...

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Bibliographic Details
Main Authors: Sudipa June Chatterjee, Ruba Halaoui, Rebecca Catherine Deagle, Carlis Rejon, Luke McCaffrey
Format: Article
Language:English
Published: The Company of Biologists 2019-05-01
Series:Biology Open
Subjects:
Mammary gland
Epithelial
Morphogenesis
Tension
E-cadherin
Online Access:http://bio.biologists.org/content/8/5/bio042341

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