Renal Contrast-enhanced Ultrasound: Clinical Applications and Emerging Researc
Contrast-enhanced ultrasound (CEUS) is an imaging modality that has achieved considerable relevance in various clinical settings including the assessment of renal disease. CEUS is performed by injecting microbubble-based ultrasound contrast agents (UCAs) that create signals to display the microvascu...
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| Format: | Article |
| Language: | English |
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Editorial Office of Advanced Ultrasound in Diagnosis and Therapy
2022-12-01
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| Series: | Advanced Ultrasound in Diagnosis and Therapy |
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| Online Access: | http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1666745525262-387437968.pdf |
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| author | Felipe Velasquez-Botero, MD, Ananya Balasubramanya, Ying Tang, MD, Qiang Lu, MD, Ji-Bin Liu, MD, John R. Eisenbrey, PhD |
| author_facet | Felipe Velasquez-Botero, MD, Ananya Balasubramanya, Ying Tang, MD, Qiang Lu, MD, Ji-Bin Liu, MD, John R. Eisenbrey, PhD |
| author_sort | Felipe Velasquez-Botero, MD, Ananya Balasubramanya, Ying Tang, MD, Qiang Lu, MD, Ji-Bin Liu, MD, John R. Eisenbrey, PhD |
| collection | DOAJ |
| description | Contrast-enhanced ultrasound (CEUS) is an imaging modality that has achieved considerable relevance in various clinical settings including the assessment of renal disease. CEUS is performed by injecting microbubble-based ultrasound contrast agents (UCAs) that create signals to display the microvasculature, allowing quantitative and qualitative assessment of parenchymal perfusion and real-time visualization of the renal anatomy. In recent years, CEUS has been widely accepted and applied for the assessment of kidney perfusion and the characterization of indeterminate renal masses, primarily due to its diagnostic efficacy, availability, low cost, reproducibility, and absence of nephrotoxicity. CEUS provides a higher spatial and temporal resolution than other cross-sectional imaging, resulting in high sensitivity and specificity for its applications in a variety of renal conditions including cancer monitoring following ablation, detection of transplant complications, hypoperfusion, acute traumatic injury, renal artery stenosis, parenchymal infection, and kidney intervention guidance. Additionally, the continuous investigation and development of new technologies surrounding this imaging technique have shown encouraging preliminary results for the use of CEUS in the evaluation of molecular expression in several disease processes, the dynamic analysis of blood flow kinetics, and the implementation of super-resolution imaging systems. The purpose of this article is to provide an overview of the current and potential clinical applications of renal CEUS. |
| first_indexed | 2024-04-12T14:43:04Z |
| format | Article |
| id | doaj.art-ff10c25947ef47569d8dd0b70f46d019 |
| institution | Directory Open Access Journal |
| issn | 2576-2516 |
| language | English |
| last_indexed | 2024-04-12T14:43:04Z |
| publishDate | 2022-12-01 |
| publisher | Editorial Office of Advanced Ultrasound in Diagnosis and Therapy |
| record_format | Article |
| series | Advanced Ultrasound in Diagnosis and Therapy |
| spelling | doaj.art-ff10c25947ef47569d8dd0b70f46d0192022-12-22T03:28:45ZengEditorial Office of Advanced Ultrasound in Diagnosis and TherapyAdvanced Ultrasound in Diagnosis and Therapy2576-25162022-12-016412914610.37015/AUDT.2022.220036Renal Contrast-enhanced Ultrasound: Clinical Applications and Emerging ResearcFelipe Velasquez-Botero, MD, Ananya Balasubramanya, Ying Tang, MD, Qiang Lu, MD, Ji-Bin Liu, MD, John R. Eisenbrey, PhD0a Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USA;b Department of Ultrasound, Tianjin Frist Central Hospital, Tianjin, China;c Department of Ultrasound, West China Hospital of Sichuan University, Chengdu, ChinaContrast-enhanced ultrasound (CEUS) is an imaging modality that has achieved considerable relevance in various clinical settings including the assessment of renal disease. CEUS is performed by injecting microbubble-based ultrasound contrast agents (UCAs) that create signals to display the microvasculature, allowing quantitative and qualitative assessment of parenchymal perfusion and real-time visualization of the renal anatomy. In recent years, CEUS has been widely accepted and applied for the assessment of kidney perfusion and the characterization of indeterminate renal masses, primarily due to its diagnostic efficacy, availability, low cost, reproducibility, and absence of nephrotoxicity. CEUS provides a higher spatial and temporal resolution than other cross-sectional imaging, resulting in high sensitivity and specificity for its applications in a variety of renal conditions including cancer monitoring following ablation, detection of transplant complications, hypoperfusion, acute traumatic injury, renal artery stenosis, parenchymal infection, and kidney intervention guidance. Additionally, the continuous investigation and development of new technologies surrounding this imaging technique have shown encouraging preliminary results for the use of CEUS in the evaluation of molecular expression in several disease processes, the dynamic analysis of blood flow kinetics, and the implementation of super-resolution imaging systems. The purpose of this article is to provide an overview of the current and potential clinical applications of renal CEUS.http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1666745525262-387437968.pdf|contrast-enhanced ultrasound|renal disease|renal ceus|emerging spplications|ceus applications |
| spellingShingle | Felipe Velasquez-Botero, MD, Ananya Balasubramanya, Ying Tang, MD, Qiang Lu, MD, Ji-Bin Liu, MD, John R. Eisenbrey, PhD Renal Contrast-enhanced Ultrasound: Clinical Applications and Emerging Researc Advanced Ultrasound in Diagnosis and Therapy |contrast-enhanced ultrasound|renal disease|renal ceus|emerging spplications|ceus applications |
| title | Renal Contrast-enhanced Ultrasound: Clinical Applications and Emerging Researc |
| title_full | Renal Contrast-enhanced Ultrasound: Clinical Applications and Emerging Researc |
| title_fullStr | Renal Contrast-enhanced Ultrasound: Clinical Applications and Emerging Researc |
| title_full_unstemmed | Renal Contrast-enhanced Ultrasound: Clinical Applications and Emerging Researc |
| title_short | Renal Contrast-enhanced Ultrasound: Clinical Applications and Emerging Researc |
| title_sort | renal contrast enhanced ultrasound clinical applications and emerging researc |
| topic | |contrast-enhanced ultrasound|renal disease|renal ceus|emerging spplications|ceus applications |
| url | http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1666745525262-387437968.pdf |
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