Social Networks and Cardiovascular Disease Events in the Jackson Heart Study
Background Cardiovascular disease (CVD) disproportionately affects Black adults. Greater social networks (SNs), or social connectedness, may lower the risk of CVD events. This study determined the association of SNs and incident CVD and tested mediation by depressive symptoms, hypertension control,...
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| Format: | Article |
| Language: | English |
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Wiley
2023-11-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.123.030149 |
| _version_ | 1797541011905314816 |
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| author | LáShauntá Glover Janiyah Sutton Emily O'Brien Mario Sims |
| author_facet | LáShauntá Glover Janiyah Sutton Emily O'Brien Mario Sims |
| author_sort | LáShauntá Glover |
| collection | DOAJ |
| description | Background Cardiovascular disease (CVD) disproportionately affects Black adults. Greater social networks (SNs), or social connectedness, may lower the risk of CVD events. This study determined the association of SNs and incident CVD and tested mediation by depressive symptoms, hypertension control, and diabetes control. Methods and Results We used the Social Network Index at exam 1 (2000–2004) to develop a continuous standardized SN score and binary categories (high versus low) among participants in the Jackson Heart Study (n=4686; mean age, 54.8 years). Surveillance of coronary heart disease, stroke, and heart failure events occurred after exam 1 (2005 for HF) until 2016. Using Cox proportional hazards regression, we estimated the association of SNs and CVD events by sex and tested the mediation of depressive symptoms, hypertension control, and diabetes control. Models adjusted for age, education, health behaviors, CVD comorbidities, and depressive symptoms. Among women, the SN score was associated with a lower hazard of stroke, coronary heart disease, and heart failure after full adjustment (hazard ratio [HR], 0.78 [95% CI, 0.64–0.95]; HR, 0.79 [95% CI, 0.71–0.88]; and HR, 0.78 [95% CI, 0.66–0.92], respectively). SN scores were also associated with a lower hazard of coronary heart disease in men (HR, 0.84 [95% CI, 0.75–0.94]) after full adjustment. High versus low SNs were associated with a lower hazard of coronary heart disease and heart failure among women after full adjustment. There was no evidence of mediation by depressive symptoms, diabetes control, and hypertension control. Conclusions Higher SNs may lower the risk of CVD events, especially in women. |
| first_indexed | 2024-03-10T13:09:15Z |
| format | Article |
| id | doaj.art-ff1749dacaab4322a0b042a72c849607 |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-03-10T13:09:15Z |
| publishDate | 2023-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-ff1749dacaab4322a0b042a72c8496072023-11-21T10:53:12ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802023-11-01122210.1161/JAHA.123.030149Social Networks and Cardiovascular Disease Events in the Jackson Heart StudyLáShauntá Glover0Janiyah Sutton1Emily O'Brien2Mario Sims3Department of Population Health Sciences Duke University School of Medicine Durham NC USAEshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill NC USADepartment of Population Health Sciences Duke University School of Medicine Durham NC USADepartment of Medicine University of Mississippi Medical Center Jackson MS USABackground Cardiovascular disease (CVD) disproportionately affects Black adults. Greater social networks (SNs), or social connectedness, may lower the risk of CVD events. This study determined the association of SNs and incident CVD and tested mediation by depressive symptoms, hypertension control, and diabetes control. Methods and Results We used the Social Network Index at exam 1 (2000–2004) to develop a continuous standardized SN score and binary categories (high versus low) among participants in the Jackson Heart Study (n=4686; mean age, 54.8 years). Surveillance of coronary heart disease, stroke, and heart failure events occurred after exam 1 (2005 for HF) until 2016. Using Cox proportional hazards regression, we estimated the association of SNs and CVD events by sex and tested the mediation of depressive symptoms, hypertension control, and diabetes control. Models adjusted for age, education, health behaviors, CVD comorbidities, and depressive symptoms. Among women, the SN score was associated with a lower hazard of stroke, coronary heart disease, and heart failure after full adjustment (hazard ratio [HR], 0.78 [95% CI, 0.64–0.95]; HR, 0.79 [95% CI, 0.71–0.88]; and HR, 0.78 [95% CI, 0.66–0.92], respectively). SN scores were also associated with a lower hazard of coronary heart disease in men (HR, 0.84 [95% CI, 0.75–0.94]) after full adjustment. High versus low SNs were associated with a lower hazard of coronary heart disease and heart failure among women after full adjustment. There was no evidence of mediation by depressive symptoms, diabetes control, and hypertension control. Conclusions Higher SNs may lower the risk of CVD events, especially in women.https://www.ahajournals.org/doi/10.1161/JAHA.123.030149Blackcardiovascular diseasesocial connectednesssocial networkswomen |
| spellingShingle | LáShauntá Glover Janiyah Sutton Emily O'Brien Mario Sims Social Networks and Cardiovascular Disease Events in the Jackson Heart Study Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Black cardiovascular disease social connectedness social networks women |
| title | Social Networks and Cardiovascular Disease Events in the Jackson Heart Study |
| title_full | Social Networks and Cardiovascular Disease Events in the Jackson Heart Study |
| title_fullStr | Social Networks and Cardiovascular Disease Events in the Jackson Heart Study |
| title_full_unstemmed | Social Networks and Cardiovascular Disease Events in the Jackson Heart Study |
| title_short | Social Networks and Cardiovascular Disease Events in the Jackson Heart Study |
| title_sort | social networks and cardiovascular disease events in the jackson heart study |
| topic | Black cardiovascular disease social connectedness social networks women |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.123.030149 |
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