Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination

The SARS-CoV-2 Omicron variant BA.2 sublineage is rapidly replacing earlier Omicron lineages, suggesting BA.2 has increased vaccine evasion properties. We measured neutralization titers of authentic BA.1 and BA.2 isolates in serum samples from persons who received the BNT162b2 booster vaccine. All...

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Main Authors: Rune M. Pedersen, Line L. Bang, Lone W. Madsen, Thomas V. Sydenham, Isik S. Johansen, Thøger G. Jensen, Ulrik S. Justesen, Thomas E. Andersen
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2022-06-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/28/6/22-0503_article
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author Rune M. Pedersen
Line L. Bang
Lone W. Madsen
Thomas V. Sydenham
Isik S. Johansen
Thøger G. Jensen
Ulrik S. Justesen
Thomas E. Andersen
author_facet Rune M. Pedersen
Line L. Bang
Lone W. Madsen
Thomas V. Sydenham
Isik S. Johansen
Thøger G. Jensen
Ulrik S. Justesen
Thomas E. Andersen
author_sort Rune M. Pedersen
collection DOAJ
description The SARS-CoV-2 Omicron variant BA.2 sublineage is rapidly replacing earlier Omicron lineages, suggesting BA.2 has increased vaccine evasion properties. We measured neutralization titers of authentic BA.1 and BA.2 isolates in serum samples from persons who received the BNT162b2 booster vaccine. All samples neutralized BA.1 and BA.2 at equal median values.
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spelling doaj.art-ff1c355ae1cd48c6a0bb24435c497fa02022-12-22T03:28:00ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592022-06-012861274127510.3201/eid2806.220503Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster VaccinationRune M. PedersenLine L. BangLone W. MadsenThomas V. SydenhamIsik S. JohansenThøger G. JensenUlrik S. JustesenThomas E. Andersen The SARS-CoV-2 Omicron variant BA.2 sublineage is rapidly replacing earlier Omicron lineages, suggesting BA.2 has increased vaccine evasion properties. We measured neutralization titers of authentic BA.1 and BA.2 isolates in serum samples from persons who received the BNT162b2 booster vaccine. All samples neutralized BA.1 and BA.2 at equal median values. https://wwwnc.cdc.gov/eid/article/28/6/22-0503_articleCOVID-19respiratory infectionssevere acute respiratory syndrome coronavirus 2SARS-CoV-2SARScoronavirus disease
spellingShingle Rune M. Pedersen
Line L. Bang
Lone W. Madsen
Thomas V. Sydenham
Isik S. Johansen
Thøger G. Jensen
Ulrik S. Justesen
Thomas E. Andersen
Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
Emerging Infectious Diseases
COVID-19
respiratory infections
severe acute respiratory syndrome coronavirus 2
SARS-CoV-2
SARS
coronavirus disease
title Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_full Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_fullStr Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_full_unstemmed Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_short Serum Neutralization of SARS-CoV-2 Omicron BA.1 and BA.2 after BNT162b2 Booster Vaccination
title_sort serum neutralization of sars cov 2 omicron ba 1 and ba 2 after bnt162b2 booster vaccination
topic COVID-19
respiratory infections
severe acute respiratory syndrome coronavirus 2
SARS-CoV-2
SARS
coronavirus disease
url https://wwwnc.cdc.gov/eid/article/28/6/22-0503_article
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