Stearic Acid and TNF-α Co-Operatively Potentiate MIP-1α Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway
Increased circulatory and adipose tissue expression of macrophage inflammatory protein (MIP)-1α (CC motif chemokine ligand-3/CCL3) and its association with inflammation in the state of obesity is well documented. Since obesity is associated with increases in both stearic acid and tumor necrosis fact...
Main Authors: | Shihab Kochumon, Hossein Arefanian, Rafaat Azim, Steve Shenouda, Texy Jacob, Nermeen Abu Khalaf, Fatema Al-Rashed, Amal Hasan, Sardar Sindhu, Fahd Al-Mulla, Rasheed Ahmad |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/8/10/403 |
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