Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study

Background: Osteoporosis (OP) patients are usually asymptomatic until osteoporotic fractures occur, which makes early diagnosis and prevention difficult, and the associated fractures secondary to OP could be preventable with appropriate management. Therefore, early identification and relevant eviden...

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Main Authors: Menghua Sun, Yili Zhang, Hao Shen, Kai Sun, Baoyu Qi, Chenchen Yu, Yingjie Zhi, Ranxing Zhang, Junjie Jiang, Yan Chai, Xu Wei, Yanming Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.544697/full
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author Menghua Sun
Yili Zhang
Hao Shen
Kai Sun
Baoyu Qi
Chenchen Yu
Yingjie Zhi
Ranxing Zhang
Junjie Jiang
Yan Chai
Xu Wei
Yanming Xie
author_facet Menghua Sun
Yili Zhang
Hao Shen
Kai Sun
Baoyu Qi
Chenchen Yu
Yingjie Zhi
Ranxing Zhang
Junjie Jiang
Yan Chai
Xu Wei
Yanming Xie
author_sort Menghua Sun
collection DOAJ
description Background: Osteoporosis (OP) patients are usually asymptomatic until osteoporotic fractures occur, which makes early diagnosis and prevention difficult, and the associated fractures secondary to OP could be preventable with appropriate management. Therefore, early identification and relevant evidence-based management of OP could guide the prevention of subsequent fractures. This study will investigate the prevalence of OP and the incidence of osteoporotic fractures in Beijing community residents to further explore the related risk factors and put forward suggestions for people aged 45–80 years old.Methods: Over 2 years, this study will conduct an OP screening and a prospective follow-up in the Beijing community to investigate the incidence of osteoporotic fractures. The study will undertake bone mineral density detection, collect biological samples, and record information via questionnaires.Discussion: The study aims to investigate the potential risk factors for osteoporosis and explore syndromes from traditional Chinese medicine that are associated with this condition based on large samples from the Beijing community. Data on the incidence of osteoporotic fractures among community dwellers in Beijing over the two-years will be available on the Chinese clinical trial registry: ChiCTR-SOC-17013090.
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spelling doaj.art-ff21fe2df7d545819928cc5b94bd6ee32022-12-21T22:32:52ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2020-12-01710.3389/fmed.2020.544697544697Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective StudyMenghua Sun0Yili Zhang1Hao Shen2Kai Sun3Baoyu Qi4Chenchen Yu5Yingjie Zhi6Ranxing Zhang7Junjie Jiang8Yan Chai9Xu Wei10Yanming Xie11Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, ChinaSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, ChinaChangxindian Community Health Service Center, Beijing, ChinaWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, ChinaWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, ChinaDepartment of Epidemiology, University of California, Los Angeles, Los Angeles, CA, United StatesWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, ChinaInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, ChinaBackground: Osteoporosis (OP) patients are usually asymptomatic until osteoporotic fractures occur, which makes early diagnosis and prevention difficult, and the associated fractures secondary to OP could be preventable with appropriate management. Therefore, early identification and relevant evidence-based management of OP could guide the prevention of subsequent fractures. This study will investigate the prevalence of OP and the incidence of osteoporotic fractures in Beijing community residents to further explore the related risk factors and put forward suggestions for people aged 45–80 years old.Methods: Over 2 years, this study will conduct an OP screening and a prospective follow-up in the Beijing community to investigate the incidence of osteoporotic fractures. The study will undertake bone mineral density detection, collect biological samples, and record information via questionnaires.Discussion: The study aims to investigate the potential risk factors for osteoporosis and explore syndromes from traditional Chinese medicine that are associated with this condition based on large samples from the Beijing community. Data on the incidence of osteoporotic fractures among community dwellers in Beijing over the two-years will be available on the Chinese clinical trial registry: ChiCTR-SOC-17013090.https://www.frontiersin.org/articles/10.3389/fmed.2020.544697/fullosteoporosisosteoporotic fracturecross-sectional studyfollow-upChinese medicine
spellingShingle Menghua Sun
Yili Zhang
Hao Shen
Kai Sun
Baoyu Qi
Chenchen Yu
Yingjie Zhi
Ranxing Zhang
Junjie Jiang
Yan Chai
Xu Wei
Yanming Xie
Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study
Frontiers in Medicine
osteoporosis
osteoporotic fracture
cross-sectional study
follow-up
Chinese medicine
title Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study
title_full Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study
title_fullStr Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study
title_full_unstemmed Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study
title_short Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study
title_sort prevalence of and risk factors for community based osteoporosis and associated fractures in beijing study protocol for a cross sectional and prospective study
topic osteoporosis
osteoporotic fracture
cross-sectional study
follow-up
Chinese medicine
url https://www.frontiersin.org/articles/10.3389/fmed.2020.544697/full
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