Rare type I CBFβ/MYH11 fusion transcript in primary acute myeloid leukemia with inv(16)(p13.1q22): a case report

Rare type I CBFβ/MYH11 fusion transcript in primary acute myeloid leukemia with inv(16)(p13.1q22): a case report

Inv(16)(p13.1q22) in acute myeloid leukemia (AML) is a common chromosomal abnormality. It leads to the core-binding factor ß-subunit (CBFβ)/smooth muscle myosin heavy chain 11 (MYH11) fusion gene. Different breakpoints were observed in the CBFβ gene at 16q22 and the MYH11 gene at 16p13.1. For this r...

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Bibliographic Details
Main Authors: Wenyi Zhang, Hainan Wang, Peilei Zhang, Hongliang Li, Xiaoli Ma, Hongxing Liu
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2021-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Acute myeloid leukemia
Type I CBFβ/MYH11
Inv(16)(p13.1q22)
Case report
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021001200501&tlng=en

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