The association between leukocytes and sperm quality is concentration dependent
<p>Abstract</p> <p>Background</p> <p>To evaluate the association between leukocytes (polymorphonuclear granulocytes -PMNL) and semen parameters at different leukocyte concentrations.</p> <p>Methods</p> <p>This was a retrospective clinical study a...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-02-01
|
| Series: | Reproductive Biology and Endocrinology |
| Online Access: | http://www.rbej.com/content/8/1/12 |
| _version_ | 1811299520997228544 |
|---|---|
| author | du Plessis Stefan S Mahfouz Reda Agarwal Ashok Lackner Jakob E Schatzl Georg |
| author_facet | du Plessis Stefan S Mahfouz Reda Agarwal Ashok Lackner Jakob E Schatzl Georg |
| author_sort | du Plessis Stefan S |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>To evaluate the association between leukocytes (polymorphonuclear granulocytes -PMNL) and semen parameters at different leukocyte concentrations.</p> <p>Methods</p> <p>This was a retrospective clinical study at a university hospital andrology clinic. Semen samples from infertile men were analyzed for sperm morphology and motility according to seminal leukocytes (PMNL) concentration (category A: >0 to <0.25 × 10(6)/mL; category B: >0.25 to <0.5 × 10(6)/mL; category C: >0.5 to <0.75 × 10(6)/mL; category D: >0.75 to <1.0 × 10(6)/mL, category E: >1 × 10(6)/mL).</p> <p>Results</p> <p>The percentage of sperm with normal morphology increased significantly from category A (14%) to category D (19%) but decreased in category E to levels (14%) similar to those in category A. Motility grades a and a+b (combined) also increased from category A (12%, 20%) to category D (18.0%, 28.5%) and decreased in category E (11%, 20.5%) to levels similar to those in category A. Sperm deformities and motility grades c and d increased progressively in all categories.</p> <p>Summary</p> <p>Leukocytes had a positive association with normal morphology and progressive motility in semen samples at a concentration of 0-1 × 10(6)/mL. The findings suggest that the association between leukocytes (PMNL) and semen quality might be concentration dependent.</p> |
| first_indexed | 2024-04-13T06:37:04Z |
| format | Article |
| id | doaj.art-ff243c825f554445a9b87a5def98ee8c |
| institution | Directory Open Access Journal |
| issn | 1477-7827 |
| language | English |
| last_indexed | 2024-04-13T06:37:04Z |
| publishDate | 2010-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Reproductive Biology and Endocrinology |
| spelling | doaj.art-ff243c825f554445a9b87a5def98ee8c2022-12-22T02:57:53ZengBMCReproductive Biology and Endocrinology1477-78272010-02-01811210.1186/1477-7827-8-12The association between leukocytes and sperm quality is concentration dependentdu Plessis Stefan SMahfouz RedaAgarwal AshokLackner Jakob ESchatzl Georg<p>Abstract</p> <p>Background</p> <p>To evaluate the association between leukocytes (polymorphonuclear granulocytes -PMNL) and semen parameters at different leukocyte concentrations.</p> <p>Methods</p> <p>This was a retrospective clinical study at a university hospital andrology clinic. Semen samples from infertile men were analyzed for sperm morphology and motility according to seminal leukocytes (PMNL) concentration (category A: >0 to <0.25 × 10(6)/mL; category B: >0.25 to <0.5 × 10(6)/mL; category C: >0.5 to <0.75 × 10(6)/mL; category D: >0.75 to <1.0 × 10(6)/mL, category E: >1 × 10(6)/mL).</p> <p>Results</p> <p>The percentage of sperm with normal morphology increased significantly from category A (14%) to category D (19%) but decreased in category E to levels (14%) similar to those in category A. Motility grades a and a+b (combined) also increased from category A (12%, 20%) to category D (18.0%, 28.5%) and decreased in category E (11%, 20.5%) to levels similar to those in category A. Sperm deformities and motility grades c and d increased progressively in all categories.</p> <p>Summary</p> <p>Leukocytes had a positive association with normal morphology and progressive motility in semen samples at a concentration of 0-1 × 10(6)/mL. The findings suggest that the association between leukocytes (PMNL) and semen quality might be concentration dependent.</p>http://www.rbej.com/content/8/1/12 |
| spellingShingle | du Plessis Stefan S Mahfouz Reda Agarwal Ashok Lackner Jakob E Schatzl Georg The association between leukocytes and sperm quality is concentration dependent Reproductive Biology and Endocrinology |
| title | The association between leukocytes and sperm quality is concentration dependent |
| title_full | The association between leukocytes and sperm quality is concentration dependent |
| title_fullStr | The association between leukocytes and sperm quality is concentration dependent |
| title_full_unstemmed | The association between leukocytes and sperm quality is concentration dependent |
| title_short | The association between leukocytes and sperm quality is concentration dependent |
| title_sort | association between leukocytes and sperm quality is concentration dependent |
| url | http://www.rbej.com/content/8/1/12 |
| work_keys_str_mv | AT duplessisstefans theassociationbetweenleukocytesandspermqualityisconcentrationdependent AT mahfouzreda theassociationbetweenleukocytesandspermqualityisconcentrationdependent AT agarwalashok theassociationbetweenleukocytesandspermqualityisconcentrationdependent AT lacknerjakobe theassociationbetweenleukocytesandspermqualityisconcentrationdependent AT schatzlgeorg theassociationbetweenleukocytesandspermqualityisconcentrationdependent AT duplessisstefans associationbetweenleukocytesandspermqualityisconcentrationdependent AT mahfouzreda associationbetweenleukocytesandspermqualityisconcentrationdependent AT agarwalashok associationbetweenleukocytesandspermqualityisconcentrationdependent AT lacknerjakobe associationbetweenleukocytesandspermqualityisconcentrationdependent AT schatzlgeorg associationbetweenleukocytesandspermqualityisconcentrationdependent |