Opioid Use Disorder Induces Oxidative Stress and Inflammation: The Attenuating Effect of Methadone Maintenance Treatment

Opioid Use Disorder Induces Oxidative Stress and Inflammation: The Attenuating Effect of Methadone Maintenance Treatment

Objective: Frequent use of opioids produces reactive oxygen species, upregulates inflammatory factors, and contributes to opiate dependence. In this study, we examined perturbations of plasma oxidative and inflammatory markers in patients with opioid use disorder in two phases. In the first phase, w...

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Bibliographic Details
Main Authors: Ali Salarian, Mehri Kadkhodaee, Maryam Zahmatkesh, Behjat Sefi, Enayatollah Bakhshi, Shahin Akhondzadeh, Soheila Adeli, Hassan Askari, Mohammad Arbabi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-02-01
Series:Iranian Journal of Psychiatry
Subjects:
Oxidative status
Opioid-use disorder
Methadone maintenance treatment
Online Access:https://ijps.tums.ac.ir/index.php/ijps/article/view/1084

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