DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY

Aim. To evaluate the heart rate variability (HRV) in patients with ischemic heart disease (IHD) and paroxysmal atrial fibrillation (AF) during atorvastatin therapy.Material and methods. 60 patients with IHD and paroxysmal AF were included in the study. Patients were divided into two groups – control...

Full description

Bibliographic Details
Main Authors: E. S. Kozlova, E. E. Galaktionova, F. A. Nemchuk, Yu. M. Lopatin
Format: Article
Language:English
Published: Столичная издательская компания 2016-01-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/1110
_version_ 1797232270486011904
author E. S. Kozlova
E. E. Galaktionova
F. A. Nemchuk
Yu. M. Lopatin
author_facet E. S. Kozlova
E. E. Galaktionova
F. A. Nemchuk
Yu. M. Lopatin
author_sort E. S. Kozlova
collection DOAJ
description Aim. To evaluate the heart rate variability (HRV) in patients with ischemic heart disease (IHD) and paroxysmal atrial fibrillation (AF) during atorvastatin therapy.Material and methods. 60 patients with IHD and paroxysmal AF were included in the study. Patients were divided into two groups – control group (basic antiarrhythmic therapy) and second group (basic antiarrhythmic therapy and atorvastatin (Liptonorm, Pharmstandart, Russia) 10mg/day). HRV was compared before and after 3 months of therapy in both groups.Results. Liptonorm significantly improved HRV indices in comparison with basic therapy alone: RMSSD increased on 33% (р <0,02), total power (TP) of spectrum on 28% (р <0,03) and high frequency (HF) component on 53 % (р <0,01).Conclusion. Liptonorm therapy improves autonomic balance in patients with IHD and paroxysmal AF.
first_indexed 2024-03-08T14:03:37Z
format Article
id doaj.art-ff2c40a371064cae8cad727ad8d01a2b
institution Directory Open Access Journal
issn 1819-6446
2225-3653
language English
last_indexed 2024-04-24T15:57:36Z
publishDate 2016-01-01
publisher Столичная издательская компания
record_format Article
series Рациональная фармакотерапия в кардиологии
spelling doaj.art-ff2c40a371064cae8cad727ad8d01a2b2024-04-01T07:43:32ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-0143333810.20996/1819-6446-2008-4-3-33-381109DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPYE. S. Kozlova0E. E. Galaktionova1F. A. Nemchuk2Yu. M. Lopatin3Volgograd State Medical University Volgograd Regional Clinical Cardiology CentreVolgograd State Medical University Volgograd Regional Clinical Cardiology CentreVolgograd State Medical University Volgograd Regional Clinical Cardiology CentreVolgograd State Medical University Volgograd Regional Clinical Cardiology CentreAim. To evaluate the heart rate variability (HRV) in patients with ischemic heart disease (IHD) and paroxysmal atrial fibrillation (AF) during atorvastatin therapy.Material and methods. 60 patients with IHD and paroxysmal AF were included in the study. Patients were divided into two groups – control group (basic antiarrhythmic therapy) and second group (basic antiarrhythmic therapy and atorvastatin (Liptonorm, Pharmstandart, Russia) 10mg/day). HRV was compared before and after 3 months of therapy in both groups.Results. Liptonorm significantly improved HRV indices in comparison with basic therapy alone: RMSSD increased on 33% (р <0,02), total power (TP) of spectrum on 28% (р <0,03) and high frequency (HF) component on 53 % (р <0,01).Conclusion. Liptonorm therapy improves autonomic balance in patients with IHD and paroxysmal AF.https://www.rpcardio.online/jour/article/view/1110heart rate variabilityischemic heart diseasestatinsаtorvastatin
spellingShingle E. S. Kozlova
E. E. Galaktionova
F. A. Nemchuk
Yu. M. Lopatin
DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY
Рациональная фармакотерапия в кардиологии
heart rate variability
ischemic heart disease
statins
аtorvastatin
title DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY
title_full DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY
title_fullStr DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY
title_full_unstemmed DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY
title_short DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY
title_sort dynamics of the heart rate variability in patients with atrial fibrillation during atorvastatin therapy
topic heart rate variability
ischemic heart disease
statins
аtorvastatin
url https://www.rpcardio.online/jour/article/view/1110
work_keys_str_mv AT eskozlova dynamicsoftheheartratevariabilityinpatientswithatrialfibrillationduringatorvastatintherapy
AT eegalaktionova dynamicsoftheheartratevariabilityinpatientswithatrialfibrillationduringatorvastatintherapy
AT fanemchuk dynamicsoftheheartratevariabilityinpatientswithatrialfibrillationduringatorvastatintherapy
AT yumlopatin dynamicsoftheheartratevariabilityinpatientswithatrialfibrillationduringatorvastatintherapy