DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY
Aim. To evaluate the heart rate variability (HRV) in patients with ischemic heart disease (IHD) and paroxysmal atrial fibrillation (AF) during atorvastatin therapy.Material and methods. 60 patients with IHD and paroxysmal AF were included in the study. Patients were divided into two groups – control...
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Столичная издательская компания
2016-01-01
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Series: | Рациональная фармакотерапия в кардиологии |
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Online Access: | https://www.rpcardio.online/jour/article/view/1110 |
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author | E. S. Kozlova E. E. Galaktionova F. A. Nemchuk Yu. M. Lopatin |
author_facet | E. S. Kozlova E. E. Galaktionova F. A. Nemchuk Yu. M. Lopatin |
author_sort | E. S. Kozlova |
collection | DOAJ |
description | Aim. To evaluate the heart rate variability (HRV) in patients with ischemic heart disease (IHD) and paroxysmal atrial fibrillation (AF) during atorvastatin therapy.Material and methods. 60 patients with IHD and paroxysmal AF were included in the study. Patients were divided into two groups – control group (basic antiarrhythmic therapy) and second group (basic antiarrhythmic therapy and atorvastatin (Liptonorm, Pharmstandart, Russia) 10mg/day). HRV was compared before and after 3 months of therapy in both groups.Results. Liptonorm significantly improved HRV indices in comparison with basic therapy alone: RMSSD increased on 33% (р <0,02), total power (TP) of spectrum on 28% (р <0,03) and high frequency (HF) component on 53 % (р <0,01).Conclusion. Liptonorm therapy improves autonomic balance in patients with IHD and paroxysmal AF. |
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id | doaj.art-ff2c40a371064cae8cad727ad8d01a2b |
institution | Directory Open Access Journal |
issn | 1819-6446 2225-3653 |
language | English |
last_indexed | 2024-04-24T15:57:36Z |
publishDate | 2016-01-01 |
publisher | Столичная издательская компания |
record_format | Article |
series | Рациональная фармакотерапия в кардиологии |
spelling | doaj.art-ff2c40a371064cae8cad727ad8d01a2b2024-04-01T07:43:32ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-0143333810.20996/1819-6446-2008-4-3-33-381109DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPYE. S. Kozlova0E. E. Galaktionova1F. A. Nemchuk2Yu. M. Lopatin3Volgograd State Medical University Volgograd Regional Clinical Cardiology CentreVolgograd State Medical University Volgograd Regional Clinical Cardiology CentreVolgograd State Medical University Volgograd Regional Clinical Cardiology CentreVolgograd State Medical University Volgograd Regional Clinical Cardiology CentreAim. To evaluate the heart rate variability (HRV) in patients with ischemic heart disease (IHD) and paroxysmal atrial fibrillation (AF) during atorvastatin therapy.Material and methods. 60 patients with IHD and paroxysmal AF were included in the study. Patients were divided into two groups – control group (basic antiarrhythmic therapy) and second group (basic antiarrhythmic therapy and atorvastatin (Liptonorm, Pharmstandart, Russia) 10mg/day). HRV was compared before and after 3 months of therapy in both groups.Results. Liptonorm significantly improved HRV indices in comparison with basic therapy alone: RMSSD increased on 33% (р <0,02), total power (TP) of spectrum on 28% (р <0,03) and high frequency (HF) component on 53 % (р <0,01).Conclusion. Liptonorm therapy improves autonomic balance in patients with IHD and paroxysmal AF.https://www.rpcardio.online/jour/article/view/1110heart rate variabilityischemic heart diseasestatinsаtorvastatin |
spellingShingle | E. S. Kozlova E. E. Galaktionova F. A. Nemchuk Yu. M. Lopatin DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY Рациональная фармакотерапия в кардиологии heart rate variability ischemic heart disease statins аtorvastatin |
title | DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY |
title_full | DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY |
title_fullStr | DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY |
title_full_unstemmed | DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY |
title_short | DYNAMICS OF THE HEART RATE VARIABILITY IN PATIENTS WITH ATRIAL FIBRILLATION DURING ATORVASTATIN THERAPY |
title_sort | dynamics of the heart rate variability in patients with atrial fibrillation during atorvastatin therapy |
topic | heart rate variability ischemic heart disease statins аtorvastatin |
url | https://www.rpcardio.online/jour/article/view/1110 |
work_keys_str_mv | AT eskozlova dynamicsoftheheartratevariabilityinpatientswithatrialfibrillationduringatorvastatintherapy AT eegalaktionova dynamicsoftheheartratevariabilityinpatientswithatrialfibrillationduringatorvastatintherapy AT fanemchuk dynamicsoftheheartratevariabilityinpatientswithatrialfibrillationduringatorvastatintherapy AT yumlopatin dynamicsoftheheartratevariabilityinpatientswithatrialfibrillationduringatorvastatintherapy |