Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status.

Mechanism of Action of Two Flavone Isomers Targeting Cancer Cells with Varying Cell Differentiation Status.

Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted by death receptor signals and bypasses the mitochondria. These two pathways...

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Main Authors: Timothy M LeJeune, Hei Yin Tsui, Laura B Parsons, Gerald E Miller, Crystal Whitted, Kayla E Lynch, Robert E Ramsauer, Jasmine U Patel, Jarrett E Wyatt, Doris S Street, Carolyn B Adams, Brian McPherson, Hei Man Tsui, Julie A Evans, Christopher Livesay, Ruben D Torrenegra, Victoria E Palau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4659548?pdf=render

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