Peripheral B cells from patients with hepatitis C virus-associated lymphoma exhibit clonal expansion and an anergic-like transcriptional profile

Peripheral B cells from patients with hepatitis C virus-associated lymphoma exhibit clonal expansion and an anergic-like transcriptional profile

Summary: Chronic HCV infection remains a global health concern due to its involvement in hepatic and extrahepatic diseases, including B cell non-Hodgkin lymphoma (BNHL). Clinical and epidemiological evidence support a causal role for HCV in BNHL development, although mechanistic insight is lacking....

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Bibliographic Details
Main Authors: Amanda N. Henning, Myagmarjav Budeebazar, Delgerbat Boldbaatar, Dahgwahdorj Yagaanbuyant, Davaadorj Duger, Khishigjargal Batsukh, Huizhi Zhou, Ryan Baumann, Robert D. Allison, Harvey J. Alter, Naranjargal Dashdorj, Valeria De Giorgi
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:iScience
Subjects:
Epigenetics
Immunology
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222020740

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