FAM21C Promotes Hepatocellular Carcinoma Invasion and Metastasis by Driving Actin Cytoskeleton Remodeling via Inhibiting Capping Ability of CAPZA1

FAM21C Promotes Hepatocellular Carcinoma Invasion and Metastasis by Driving Actin Cytoskeleton Remodeling via Inhibiting Capping Ability of CAPZA1

Hepatocellular carcinoma (HCC) is characterized by a high incidence of metastasis. The dynamic remodeling of the actin cytoskeleton plays an important role in the invasion and migration of HCC cells. In previous studies, we found that CAPZA1, a capping protein, can promote EMT of HCC cells by regula...

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Bibliographic Details
Main Authors: Yao Lu, Deng Huang, Baolin Wang, Bowen Zheng, Jialong Liu, Juxian Song, Shuguo Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
FAM21C
CAPZA1
actin cytoskeleton
invasion and metastasis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.809195/full

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