Diabetic Wound Healing Activity of Anabas testudineus Fish Scales
Background: Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing. Objective: This study aimed to ext...
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Format: | Article |
Language: | English |
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Universitas Muhammadiyah Semarang
2023-02-01
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Series: | Magna Medika |
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Online Access: | https://jurnal.unimus.ac.id/index.php/APKKM/article/view/10853 |
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author | Erwin Rosadi Lia Yulia Budiarti Bhisma Ridho Romadhon Nida Nurkhalishah Nur Salsabila Apriliani Risma Putri Nur Azmina Aisyah Isnaini Isnaini |
author_facet | Erwin Rosadi Lia Yulia Budiarti Bhisma Ridho Romadhon Nida Nurkhalishah Nur Salsabila Apriliani Risma Putri Nur Azmina Aisyah Isnaini Isnaini |
author_sort | Erwin Rosadi |
collection | DOAJ |
description | Background: Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing.
Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gel
Methods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%.
Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%.
Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results. |
first_indexed | 2024-04-10T07:13:34Z |
format | Article |
id | doaj.art-ff36cb6187b0473d968d4407575ffcd9 |
institution | Directory Open Access Journal |
issn | 2407-0505 2774-2318 |
language | English |
last_indexed | 2024-04-10T07:13:34Z |
publishDate | 2023-02-01 |
publisher | Universitas Muhammadiyah Semarang |
record_format | Article |
series | Magna Medika |
spelling | doaj.art-ff36cb6187b0473d968d4407575ffcd92023-02-26T06:46:06ZengUniversitas Muhammadiyah SemarangMagna Medika2407-05052774-23182023-02-01101404710.26714/magnamed.10.1.2023.40-476376Diabetic Wound Healing Activity of Anabas testudineus Fish ScalesErwin Rosadi0Lia Yulia Budiarti1Bhisma Ridho Romadhon2Nida Nurkhalishah3Nur Salsabila Apriliani Risma Putri4Nur Azmina Aisyah5Isnaini Isnaini6Faculty of Fishery and Marine University of Lambung MangkuratFaculty of Medicine University of Lambung MangkuratFaculty of Medicine University of Lambung MangkuratFaculty of Medicine University of Lambung MangkuratFaculty of Medicine University of Lambung MangkuratSepuluh Nopember Institute of Technology[Scopus ID: 57204801189] FK Universitas Lambung Mangkurat, BanjarmasinBackground: Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing. Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gel Methods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%. Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%. Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results.https://jurnal.unimus.ac.id/index.php/APKKM/article/view/10853chitosanftirwound healinganabas testudineus |
spellingShingle | Erwin Rosadi Lia Yulia Budiarti Bhisma Ridho Romadhon Nida Nurkhalishah Nur Salsabila Apriliani Risma Putri Nur Azmina Aisyah Isnaini Isnaini Diabetic Wound Healing Activity of Anabas testudineus Fish Scales Magna Medika chitosan ftir wound healing anabas testudineus |
title | Diabetic Wound Healing Activity of Anabas testudineus Fish Scales |
title_full | Diabetic Wound Healing Activity of Anabas testudineus Fish Scales |
title_fullStr | Diabetic Wound Healing Activity of Anabas testudineus Fish Scales |
title_full_unstemmed | Diabetic Wound Healing Activity of Anabas testudineus Fish Scales |
title_short | Diabetic Wound Healing Activity of Anabas testudineus Fish Scales |
title_sort | diabetic wound healing activity of anabas testudineus fish scales |
topic | chitosan ftir wound healing anabas testudineus |
url | https://jurnal.unimus.ac.id/index.php/APKKM/article/view/10853 |
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