Diabetic Wound Healing Activity of Anabas testudineus Fish Scales

Background:  Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing. Objective: This study aimed to ext...

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Main Authors: Erwin Rosadi, Lia Yulia Budiarti, Bhisma Ridho Romadhon, Nida Nurkhalishah, Nur Salsabila Apriliani Risma Putri, Nur Azmina Aisyah, Isnaini Isnaini
Format: Article
Language:English
Published: Universitas Muhammadiyah Semarang 2023-02-01
Series:Magna Medika
Subjects:
Online Access:https://jurnal.unimus.ac.id/index.php/APKKM/article/view/10853
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author Erwin Rosadi
Lia Yulia Budiarti
Bhisma Ridho Romadhon
Nida Nurkhalishah
Nur Salsabila Apriliani Risma Putri
Nur Azmina Aisyah
Isnaini Isnaini
author_facet Erwin Rosadi
Lia Yulia Budiarti
Bhisma Ridho Romadhon
Nida Nurkhalishah
Nur Salsabila Apriliani Risma Putri
Nur Azmina Aisyah
Isnaini Isnaini
author_sort Erwin Rosadi
collection DOAJ
description Background:  Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing. Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gel Methods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%. Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%. Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results.
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spelling doaj.art-ff36cb6187b0473d968d4407575ffcd92023-02-26T06:46:06ZengUniversitas Muhammadiyah SemarangMagna Medika2407-05052774-23182023-02-01101404710.26714/magnamed.10.1.2023.40-476376Diabetic Wound Healing Activity of Anabas testudineus Fish ScalesErwin Rosadi0Lia Yulia Budiarti1Bhisma Ridho Romadhon2Nida Nurkhalishah3Nur Salsabila Apriliani Risma Putri4Nur Azmina Aisyah5Isnaini Isnaini6Faculty of Fishery and Marine University of Lambung MangkuratFaculty of Medicine University of Lambung MangkuratFaculty of Medicine University of Lambung MangkuratFaculty of Medicine University of Lambung MangkuratFaculty of Medicine University of Lambung MangkuratSepuluh Nopember Institute of Technology[Scopus ID: 57204801189] FK Universitas Lambung Mangkurat, BanjarmasinBackground:  Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing. Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gel Methods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%. Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%. Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results.https://jurnal.unimus.ac.id/index.php/APKKM/article/view/10853chitosanftirwound healinganabas testudineus
spellingShingle Erwin Rosadi
Lia Yulia Budiarti
Bhisma Ridho Romadhon
Nida Nurkhalishah
Nur Salsabila Apriliani Risma Putri
Nur Azmina Aisyah
Isnaini Isnaini
Diabetic Wound Healing Activity of Anabas testudineus Fish Scales
Magna Medika
chitosan
ftir
wound healing
anabas testudineus
title Diabetic Wound Healing Activity of Anabas testudineus Fish Scales
title_full Diabetic Wound Healing Activity of Anabas testudineus Fish Scales
title_fullStr Diabetic Wound Healing Activity of Anabas testudineus Fish Scales
title_full_unstemmed Diabetic Wound Healing Activity of Anabas testudineus Fish Scales
title_short Diabetic Wound Healing Activity of Anabas testudineus Fish Scales
title_sort diabetic wound healing activity of anabas testudineus fish scales
topic chitosan
ftir
wound healing
anabas testudineus
url https://jurnal.unimus.ac.id/index.php/APKKM/article/view/10853
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