Differences in spontaneous speech fluency between Parkinson's disease and spinocerebellar ataxia type 3

BackgroundThe basal ganglia and cerebellum both have a role in speech production although the effect of isolated involvement of these structures on speech fluency remains unclear.ObjectiveThe study aimed to assess the differences in the articulatory pattern in patients with cerebellar vs. basal gang...

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Main Authors: Vanessa Brzoskowski dos Santos, Annelise Ayres, Maiara Laís Mallmann Kieling, Elaine Cristina Miglorini, Laura Bannach Jardim, Artur Francisco Schumacher-Schuh, Carlos Roberto de Mello Rieder, Raphael Machado de Castilhos, Kristie Spencer, Rui Rothe-Neves, Maira Rozenfeld Olchik
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1179287/full
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author Vanessa Brzoskowski dos Santos
Vanessa Brzoskowski dos Santos
Annelise Ayres
Maiara Laís Mallmann Kieling
Maiara Laís Mallmann Kieling
Elaine Cristina Miglorini
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Artur Francisco Schumacher-Schuh
Artur Francisco Schumacher-Schuh
Carlos Roberto de Mello Rieder
Raphael Machado de Castilhos
Raphael Machado de Castilhos
Kristie Spencer
Rui Rothe-Neves
Maira Rozenfeld Olchik
Maira Rozenfeld Olchik
Maira Rozenfeld Olchik
author_facet Vanessa Brzoskowski dos Santos
Vanessa Brzoskowski dos Santos
Annelise Ayres
Maiara Laís Mallmann Kieling
Maiara Laís Mallmann Kieling
Elaine Cristina Miglorini
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Artur Francisco Schumacher-Schuh
Artur Francisco Schumacher-Schuh
Carlos Roberto de Mello Rieder
Raphael Machado de Castilhos
Raphael Machado de Castilhos
Kristie Spencer
Rui Rothe-Neves
Maira Rozenfeld Olchik
Maira Rozenfeld Olchik
Maira Rozenfeld Olchik
author_sort Vanessa Brzoskowski dos Santos
collection DOAJ
description BackgroundThe basal ganglia and cerebellum both have a role in speech production although the effect of isolated involvement of these structures on speech fluency remains unclear.ObjectiveThe study aimed to assess the differences in the articulatory pattern in patients with cerebellar vs. basal ganglia disorders.MethodsA total of 20 individuals with Parkinson's disease (PD), 20 with spinocerebellar ataxia type 3 (SCA3), and 40 controls (control group, CG) were included. Diadochokinesis (DDK) and monolog tasks were collected.ResultsThe only variable that distinguished SCA3 carriers from the CG was the number of syllables in the monolog, with SCA3 patients of a significantly lower number. For patients with PD, the number of syllables, phonation time, DDK, and monolog were significantly lower than for CG. Patients with PD were significantly worse compared to patients with SCA3 in the number of syllables and phonation time in DDK, and phonation time in monolog. Additionally, there was a significant correlation between the number of syllables in the monolog and the MDS-UPDRS III for participants with PD, and the Friedreich Ataxia Rating Scale for participants with SCA3 suggesting a relationship between speech and general motor functioning.ConclusionThe monolog task is better at discriminating individuals with cerebellar vs. Parkinson's diseases as well as differentiating healthy control and was related to the severity of the disease.
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spelling doaj.art-ff36fd9dd1ff40adbb07c790a77a1ca12023-05-05T05:57:57ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-05-011410.3389/fneur.2023.11792871179287Differences in spontaneous speech fluency between Parkinson's disease and spinocerebellar ataxia type 3Vanessa Brzoskowski dos Santos0Vanessa Brzoskowski dos Santos1Annelise Ayres2Maiara Laís Mallmann Kieling3Maiara Laís Mallmann Kieling4Elaine Cristina Miglorini5Laura Bannach Jardim6Laura Bannach Jardim7Laura Bannach Jardim8Laura Bannach Jardim9Laura Bannach Jardim10Artur Francisco Schumacher-Schuh11Artur Francisco Schumacher-Schuh12Carlos Roberto de Mello Rieder13Raphael Machado de Castilhos14Raphael Machado de Castilhos15Kristie Spencer16Rui Rothe-Neves17Maira Rozenfeld Olchik18Maira Rozenfeld Olchik19Maira Rozenfeld Olchik20Post-graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilNeurology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, BrazilNeurology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, BrazilPost-graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilNeurology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, BrazilPost-graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilPost-graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilNeurology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, BrazilPost-graduate Program in Genetics and Molecular Biology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilMedical Genetics Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, BrazilDepartment of Internal Medicine, University of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilPost-graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilDepartment of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilPost-Graduate Program in Rehabilitation Sciences, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, BrazilPost-graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilDepartment of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilDepartment of Speech and Hearing Sciences, University of Washington, Seattle, WA, United StatesPhonetics Laboratory of the Faculty of Letters, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BrazilPost-graduate Program in Medicine: Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilNeurology Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil0Department of Surgery and Orthopedics, Faculdade de Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, BrazilBackgroundThe basal ganglia and cerebellum both have a role in speech production although the effect of isolated involvement of these structures on speech fluency remains unclear.ObjectiveThe study aimed to assess the differences in the articulatory pattern in patients with cerebellar vs. basal ganglia disorders.MethodsA total of 20 individuals with Parkinson's disease (PD), 20 with spinocerebellar ataxia type 3 (SCA3), and 40 controls (control group, CG) were included. Diadochokinesis (DDK) and monolog tasks were collected.ResultsThe only variable that distinguished SCA3 carriers from the CG was the number of syllables in the monolog, with SCA3 patients of a significantly lower number. For patients with PD, the number of syllables, phonation time, DDK, and monolog were significantly lower than for CG. Patients with PD were significantly worse compared to patients with SCA3 in the number of syllables and phonation time in DDK, and phonation time in monolog. Additionally, there was a significant correlation between the number of syllables in the monolog and the MDS-UPDRS III for participants with PD, and the Friedreich Ataxia Rating Scale for participants with SCA3 suggesting a relationship between speech and general motor functioning.ConclusionThe monolog task is better at discriminating individuals with cerebellar vs. Parkinson's diseases as well as differentiating healthy control and was related to the severity of the disease.https://www.frontiersin.org/articles/10.3389/fneur.2023.1179287/fullParkinson's diseasespinocerebellar ataxiaspeech disordersdysarthriaarticulation disorders
spellingShingle Vanessa Brzoskowski dos Santos
Vanessa Brzoskowski dos Santos
Annelise Ayres
Maiara Laís Mallmann Kieling
Maiara Laís Mallmann Kieling
Elaine Cristina Miglorini
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Laura Bannach Jardim
Artur Francisco Schumacher-Schuh
Artur Francisco Schumacher-Schuh
Carlos Roberto de Mello Rieder
Raphael Machado de Castilhos
Raphael Machado de Castilhos
Kristie Spencer
Rui Rothe-Neves
Maira Rozenfeld Olchik
Maira Rozenfeld Olchik
Maira Rozenfeld Olchik
Differences in spontaneous speech fluency between Parkinson's disease and spinocerebellar ataxia type 3
Frontiers in Neurology
Parkinson's disease
spinocerebellar ataxia
speech disorders
dysarthria
articulation disorders
title Differences in spontaneous speech fluency between Parkinson's disease and spinocerebellar ataxia type 3
title_full Differences in spontaneous speech fluency between Parkinson's disease and spinocerebellar ataxia type 3
title_fullStr Differences in spontaneous speech fluency between Parkinson's disease and spinocerebellar ataxia type 3
title_full_unstemmed Differences in spontaneous speech fluency between Parkinson's disease and spinocerebellar ataxia type 3
title_short Differences in spontaneous speech fluency between Parkinson's disease and spinocerebellar ataxia type 3
title_sort differences in spontaneous speech fluency between parkinson s disease and spinocerebellar ataxia type 3
topic Parkinson's disease
spinocerebellar ataxia
speech disorders
dysarthria
articulation disorders
url https://www.frontiersin.org/articles/10.3389/fneur.2023.1179287/full
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