Exploitation of Mangrove Endophytic Fungi for Infectious Disease Drug Discovery

Exploitation of Mangrove Endophytic Fungi for Infectious Disease Drug Discovery

There is an acute need for new and effective agents to treat infectious diseases. We conducted a screening program to assess the potential of mangrove-derived endophytic fungi as a source of new antibiotics. Fungi cultured in the presence and absence of small molecule epigenetic modulators were scre...

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Bibliographic Details
Main Authors: Danielle H. Demers, Matthew A. Knestrick, Renee Fleeman, Rahmy Tawfik, Ala Azhari, Ashley Souza, Brian Vesely, Mandy Netherton, Rashmi Gupta, Beatrice L. Colon, Christopher A. Rice, Mario A. Rodríguez-Pérez, Kyle H. Rohde, Dennis E. Kyle, Lindsey N. Shaw, Bill J. Baker
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Marine Drugs
Subjects:
endophytic fungi
epigenetic modification
mangroves
screening
infectious disease drug discovery
Online Access:http://www.mdpi.com/1660-3397/16/10/376

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