Endoscopic Ultrasound-Guided Random Omental Fine Needle Aspiration: A Novel Technique for the Diagnosis of Peritoneal Carcinomatosis
Background/Aims Diagnostic abdominal paracentesis has been described in literature to have variable sensitivity of 50%–75% for the detection of peritoneal carcinomatosis (PC). We believe that random needle aspirates from the omentum, even in the absence of obvious deposits by endoscopic ultrasound (...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2020-09-01
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| Series: | Clinical Endoscopy |
| Subjects: | |
| Online Access: | http://www.e-ce.org/upload/pdf/ce-2019-175.pdf |
| _version_ | 1797668678493274112 |
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| author | Pradeep Kumar Siddappa Neha Jain Naveen K. Agarwal Monika Jain Gurwant Singh Lamba |
| author_facet | Pradeep Kumar Siddappa Neha Jain Naveen K. Agarwal Monika Jain Gurwant Singh Lamba |
| author_sort | Pradeep Kumar Siddappa |
| collection | DOAJ |
| description | Background/Aims Diagnostic abdominal paracentesis has been described in literature to have variable sensitivity of 50%–75% for the detection of peritoneal carcinomatosis (PC). We believe that random needle aspirates from the omentum, even in the absence of obvious deposits by endoscopic ultrasound (EUS), could prove malignancy in patients with PC. Methods Consecutive patients who underwent EUS for diagnosis and staging of cancer and found to have ascites were included after obtaining informed consent. EUS-guided fine needle aspiration (EUS-FNA) from random sites in the omentum was performed through the transgastric route using a linear echoendoscope. Results Fifty-four patients underwent EUS during October 2015 to April 2017 for detection, staging, or FNA of a suspected malignant lesion. Ascites was seen in 17 patients and 15 patients who fulfilled the criteria were included. The procedure was successful in all patients. Cytology was suggestive of malignancy in 12 (80%) but not suggestive of malignancy in 3 (20%) patients. Three patients who tested negative had hyperbilirubinemia with biliary obstruction. Their ascitic fluid analysis result was also negative. Conclusions Random FNA of the omentum in patients with malignancy-related ascites is highly effective in the diagnosis of PC and could be employed during EUS evaluation of malignancies. |
| first_indexed | 2024-03-11T20:31:53Z |
| format | Article |
| id | doaj.art-ff3b9186713f4afd83430b2e5dfd5dd2 |
| institution | Directory Open Access Journal |
| issn | 2234-2400 2234-2443 |
| language | English |
| last_indexed | 2024-03-11T20:31:53Z |
| publishDate | 2020-09-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj.art-ff3b9186713f4afd83430b2e5dfd5dd22023-10-02T08:12:05ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432020-09-0153559459910.5946/ce.2019.1757413Endoscopic Ultrasound-Guided Random Omental Fine Needle Aspiration: A Novel Technique for the Diagnosis of Peritoneal CarcinomatosisPradeep Kumar Siddappa0Neha Jain1Naveen K. Agarwal2Monika Jain3Gurwant Singh Lamba4 Department of Gastroenterology, Sri Balaji Action Medical Institute, New Delhi, India Department of Gastroenterology, Sri Balaji Action Medical Institute, New Delhi, India Department of Pathology, Action Cancer Hospital, New Delhi, India Department of Gastroenterology, Sri Balaji Action Medical Institute, New Delhi, India Department of Gastroenterology, Sri Balaji Action Medical Institute, New Delhi, IndiaBackground/Aims Diagnostic abdominal paracentesis has been described in literature to have variable sensitivity of 50%–75% for the detection of peritoneal carcinomatosis (PC). We believe that random needle aspirates from the omentum, even in the absence of obvious deposits by endoscopic ultrasound (EUS), could prove malignancy in patients with PC. Methods Consecutive patients who underwent EUS for diagnosis and staging of cancer and found to have ascites were included after obtaining informed consent. EUS-guided fine needle aspiration (EUS-FNA) from random sites in the omentum was performed through the transgastric route using a linear echoendoscope. Results Fifty-four patients underwent EUS during October 2015 to April 2017 for detection, staging, or FNA of a suspected malignant lesion. Ascites was seen in 17 patients and 15 patients who fulfilled the criteria were included. The procedure was successful in all patients. Cytology was suggestive of malignancy in 12 (80%) but not suggestive of malignancy in 3 (20%) patients. Three patients who tested negative had hyperbilirubinemia with biliary obstruction. Their ascitic fluid analysis result was also negative. Conclusions Random FNA of the omentum in patients with malignancy-related ascites is highly effective in the diagnosis of PC and could be employed during EUS evaluation of malignancies.http://www.e-ce.org/upload/pdf/ce-2019-175.pdfascitesendoscopic ultrasoundendoscopic ultrasound-guided fine needle aspirationomentumperitoneal neoplasms |
| spellingShingle | Pradeep Kumar Siddappa Neha Jain Naveen K. Agarwal Monika Jain Gurwant Singh Lamba Endoscopic Ultrasound-Guided Random Omental Fine Needle Aspiration: A Novel Technique for the Diagnosis of Peritoneal Carcinomatosis Clinical Endoscopy ascites endoscopic ultrasound endoscopic ultrasound-guided fine needle aspiration omentum peritoneal neoplasms |
| title | Endoscopic Ultrasound-Guided Random Omental Fine Needle Aspiration: A Novel Technique for the Diagnosis of Peritoneal Carcinomatosis |
| title_full | Endoscopic Ultrasound-Guided Random Omental Fine Needle Aspiration: A Novel Technique for the Diagnosis of Peritoneal Carcinomatosis |
| title_fullStr | Endoscopic Ultrasound-Guided Random Omental Fine Needle Aspiration: A Novel Technique for the Diagnosis of Peritoneal Carcinomatosis |
| title_full_unstemmed | Endoscopic Ultrasound-Guided Random Omental Fine Needle Aspiration: A Novel Technique for the Diagnosis of Peritoneal Carcinomatosis |
| title_short | Endoscopic Ultrasound-Guided Random Omental Fine Needle Aspiration: A Novel Technique for the Diagnosis of Peritoneal Carcinomatosis |
| title_sort | endoscopic ultrasound guided random omental fine needle aspiration a novel technique for the diagnosis of peritoneal carcinomatosis |
| topic | ascites endoscopic ultrasound endoscopic ultrasound-guided fine needle aspiration omentum peritoneal neoplasms |
| url | http://www.e-ce.org/upload/pdf/ce-2019-175.pdf |
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