Binding-Induced Diversity of a Human Telomeric G-Quadruplex Stability Phase Space
The structural polymorphism of G-quadruplex nucleic acids is an important factor in their recognition by proteins and small-molecule ligands. However, it is not clear why the binding of several ligands alters G-quadruplex topology. We addressed this question by following the (un)folding and binding...
| Príomhchruthaitheoirí: | , , , |
|---|---|
| Formáid: | Alt |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
MDPI AG
2022-09-01
|
| Sraith: | Pharmaceuticals |
| Ábhair: | |
| Rochtain ar líne: | https://www.mdpi.com/1424-8247/15/9/1150 |