Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?

The insula is a significant neural region associated with the development and clinical symptoms of schizophrenia. Here, we provide an overview of the role of the insula in a non-pathological context, as well as its function in schizophrenia, discussing how structural and functional changes to the in...

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Main Authors: Susanna Gebhardt, Henry A. Nasrallah
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Biomarkers in Neuropsychiatry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666144624000042
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author Susanna Gebhardt
Henry A. Nasrallah
author_facet Susanna Gebhardt
Henry A. Nasrallah
author_sort Susanna Gebhardt
collection DOAJ
description The insula is a significant neural region associated with the development and clinical symptoms of schizophrenia. Here, we provide an overview of the role of the insula in a non-pathological context, as well as its function in schizophrenia, discussing how structural and functional changes to the insula can provide insight into the etiology of schizophrenia and contribute to potential therapeutic intervention.
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spelling doaj.art-ff3d8170a7ea4fb296821eba0782c9462024-06-16T05:46:48ZengElsevierBiomarkers in Neuropsychiatry2666-14462024-06-0110100086Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?Susanna Gebhardt0Henry A. Nasrallah1Corresponding author.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, USADepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, USAThe insula is a significant neural region associated with the development and clinical symptoms of schizophrenia. Here, we provide an overview of the role of the insula in a non-pathological context, as well as its function in schizophrenia, discussing how structural and functional changes to the insula can provide insight into the etiology of schizophrenia and contribute to potential therapeutic intervention.http://www.sciencedirect.com/science/article/pii/S2666144624000042SchizophreniaInsulaNeurodevelopment
spellingShingle Susanna Gebhardt
Henry A. Nasrallah
Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?
Biomarkers in Neuropsychiatry
Schizophrenia
Insula
Neurodevelopment
title Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?
title_full Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?
title_fullStr Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?
title_full_unstemmed Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?
title_short Are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk?
title_sort are neurodevelopmental structural pathologies of the insula potential biomarkers for schizophrenia risk
topic Schizophrenia
Insula
Neurodevelopment
url http://www.sciencedirect.com/science/article/pii/S2666144624000042
work_keys_str_mv AT susannagebhardt areneurodevelopmentalstructuralpathologiesoftheinsulapotentialbiomarkersforschizophreniarisk
AT henryanasrallah areneurodevelopmentalstructuralpathologiesoftheinsulapotentialbiomarkersforschizophreniarisk