The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip

Cancer is an abnormal cell growth which tends to proliferate in an uncontrolled way and, in some cases, leads to metastasis. If cancer is left untreated, it can immediately cause death. The use of magnetic nanoparticles (MNPs) as a drug delivery system will enable drugs to target tissues and cell ty...

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Main Authors: Ali Alirezaie Alavijeh, Mohammad Barati, Meisam Barati, Hussein Abbasi Dehkordi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2019-08-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-25289
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author Ali Alirezaie Alavijeh
Mohammad Barati
Meisam Barati
Hussein Abbasi Dehkordi
author_facet Ali Alirezaie Alavijeh
Mohammad Barati
Meisam Barati
Hussein Abbasi Dehkordi
author_sort Ali Alirezaie Alavijeh
collection DOAJ
description Cancer is an abnormal cell growth which tends to proliferate in an uncontrolled way and, in some cases, leads to metastasis. If cancer is left untreated, it can immediately cause death. The use of magnetic nanoparticles (MNPs) as a drug delivery system will enable drugs to target tissues and cell types precisely. This study describes usual strategies and consideration for the synthesis of MNPs and incorporates payload drug on MNPs. They have advantages such as visual targeting and delivering which will be discussed in this review. In addition, we considered body magnetic field to make drug delivery process more effective and safer by the application of MNPs and tumor-on-chip.
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spelling doaj.art-ff4055f6491348959c9216fd395c83422022-12-22T01:48:55ZengTabriz University of Medical SciencesAdvanced Pharmaceutical Bulletin2228-58812251-73082019-08-019336037310.15171/apb.2019.043apb-25289The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-ChipAli Alirezaie Alavijeh0Mohammad Barati1Meisam Barati2Hussein Abbasi Dehkordi3Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.Department of Applied Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran.Student Research Committee, Department of Cellular and Molecular Nutrition, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.Cancer is an abnormal cell growth which tends to proliferate in an uncontrolled way and, in some cases, leads to metastasis. If cancer is left untreated, it can immediately cause death. The use of magnetic nanoparticles (MNPs) as a drug delivery system will enable drugs to target tissues and cell types precisely. This study describes usual strategies and consideration for the synthesis of MNPs and incorporates payload drug on MNPs. They have advantages such as visual targeting and delivering which will be discussed in this review. In addition, we considered body magnetic field to make drug delivery process more effective and safer by the application of MNPs and tumor-on-chip.https://apb.tbzmed.ac.ir/PDF/apb-25289Body magnetic fieldsCancerDrug deliveryMagnetic nanoparticles
spellingShingle Ali Alirezaie Alavijeh
Mohammad Barati
Meisam Barati
Hussein Abbasi Dehkordi
The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip
Advanced Pharmaceutical Bulletin
Body magnetic fields
Cancer
Drug delivery
Magnetic nanoparticles
title The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip
title_full The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip
title_fullStr The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip
title_full_unstemmed The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip
title_short The Potential of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer Based on Body Magnetic Field and Organ-on-the-Chip
title_sort potential of magnetic nanoparticles for diagnosis and treatment of cancer based on body magnetic field and organ on the chip
topic Body magnetic fields
Cancer
Drug delivery
Magnetic nanoparticles
url https://apb.tbzmed.ac.ir/PDF/apb-25289
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