Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPD
Abstract We examined the performance of a commercially-available handheld bioimpedance (BIA) device relative to dual X-ray absorptiometry (DXA) to assess body composition differences among Veterans with chronic obstructive pulmonary disease (COPD). Body composition was measured using DXA and BIA (Om...
| Main Authors: | , , , , , |
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| Format: | Article |
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Nature Portfolio
2022-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-05887-4 |
| _version_ | 1818887673736069120 |
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| author | Paola N. Cruz Rivera Rebekah L. Goldstein Madeline Polak Antonio A. Lazzari Marilyn L. Moy Emily S. Wan |
| author_facet | Paola N. Cruz Rivera Rebekah L. Goldstein Madeline Polak Antonio A. Lazzari Marilyn L. Moy Emily S. Wan |
| author_sort | Paola N. Cruz Rivera |
| collection | DOAJ |
| description | Abstract We examined the performance of a commercially-available handheld bioimpedance (BIA) device relative to dual X-ray absorptiometry (DXA) to assess body composition differences among Veterans with chronic obstructive pulmonary disease (COPD). Body composition was measured using DXA and BIA (Omron HBF-306C) at a single time point. Correlations between BIA- and DXA-assessed percent fat, fat mass, and fat-free mass were analyzed using Spearman (ρ) and Lin Concordance Correlation Coefficients (ρc). Mean differences in fat mass were visualized using Bland–Altman plots. Subgroup analyses by obesity status (BMI < 30 versus ≥ 30) were performed. Among 50 participants (96% male; mean age: 69.5 ± 6.0 years), BIA-assessed fat mass was strongly correlated (ρ = 0.94) and demonstrate excellent concordance (ρc = 0.95, [95%CI: 0.93–0.98]) with DXA, with a mean difference of 2.7 ± 3.2 kg between BIA and DXA. Although Spearman correlations between BIA- and DXA-assessed percent fat and fat-free mass were strong (ρ = 0.8 and 0.91, respectively), concordance values were only moderate (ρc = 0.67 and 0.74, respectively). Significantly stronger correlations were observed for obese relative to non-obese subjects for total percent fat (ρobese = 0.85 versus ρnon-obese = 0.5) and fat mass (ρobese = 0.96 versus ρnon-obese = 0.84). A handheld BIA device demonstrated high concordance with DXA for fat mass and moderate concordance for total percent fat and fat-free mass. ClinicalTrials.gov: NCT02099799. |
| first_indexed | 2024-12-19T16:40:58Z |
| format | Article |
| id | doaj.art-ff41bd6f0fbc4666a4ed1d7db37a4f76 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-19T16:40:58Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-ff41bd6f0fbc4666a4ed1d7db37a4f762022-12-21T20:13:48ZengNature PortfolioScientific Reports2045-23222022-02-011211810.1038/s41598-022-05887-4Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPDPaola N. Cruz Rivera0Rebekah L. Goldstein1Madeline Polak2Antonio A. Lazzari3Marilyn L. Moy4Emily S. Wan5Pulmonary, Allergy, Sleep and Critical Care Medicine Section, VA Boston Healthcare SystemPulmonary, Allergy, Sleep and Critical Care Medicine Section, VA Boston Healthcare SystemPulmonary, Allergy, Sleep and Critical Care Medicine Section, VA Boston Healthcare SystemPrimary Care and Rheumatology Sections, VA Boston Healthcare SystemPulmonary, Allergy, Sleep and Critical Care Medicine Section, VA Boston Healthcare SystemPulmonary, Allergy, Sleep and Critical Care Medicine Section, VA Boston Healthcare SystemAbstract We examined the performance of a commercially-available handheld bioimpedance (BIA) device relative to dual X-ray absorptiometry (DXA) to assess body composition differences among Veterans with chronic obstructive pulmonary disease (COPD). Body composition was measured using DXA and BIA (Omron HBF-306C) at a single time point. Correlations between BIA- and DXA-assessed percent fat, fat mass, and fat-free mass were analyzed using Spearman (ρ) and Lin Concordance Correlation Coefficients (ρc). Mean differences in fat mass were visualized using Bland–Altman plots. Subgroup analyses by obesity status (BMI < 30 versus ≥ 30) were performed. Among 50 participants (96% male; mean age: 69.5 ± 6.0 years), BIA-assessed fat mass was strongly correlated (ρ = 0.94) and demonstrate excellent concordance (ρc = 0.95, [95%CI: 0.93–0.98]) with DXA, with a mean difference of 2.7 ± 3.2 kg between BIA and DXA. Although Spearman correlations between BIA- and DXA-assessed percent fat and fat-free mass were strong (ρ = 0.8 and 0.91, respectively), concordance values were only moderate (ρc = 0.67 and 0.74, respectively). Significantly stronger correlations were observed for obese relative to non-obese subjects for total percent fat (ρobese = 0.85 versus ρnon-obese = 0.5) and fat mass (ρobese = 0.96 versus ρnon-obese = 0.84). A handheld BIA device demonstrated high concordance with DXA for fat mass and moderate concordance for total percent fat and fat-free mass. ClinicalTrials.gov: NCT02099799.https://doi.org/10.1038/s41598-022-05887-4 |
| spellingShingle | Paola N. Cruz Rivera Rebekah L. Goldstein Madeline Polak Antonio A. Lazzari Marilyn L. Moy Emily S. Wan Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPD Scientific Reports |
| title | Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPD |
| title_full | Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPD |
| title_fullStr | Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPD |
| title_full_unstemmed | Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPD |
| title_short | Performance of bioelectrical impedance analysis compared to dual X-ray absorptiometry (DXA) in Veterans with COPD |
| title_sort | performance of bioelectrical impedance analysis compared to dual x ray absorptiometry dxa in veterans with copd |
| url | https://doi.org/10.1038/s41598-022-05887-4 |
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