Accumulation of formaldehyde causes motor deficits in an in vivo model of hindlimb unloading

Accumulation of formaldehyde causes motor deficits in an in vivo model of hindlimb unloading

Dandan Yao et al. demonstrated that accumulation of formaldehyde in the cerebellum and skeletal muscle contributed toward motor deficits in a mouse model of hindlimb unloading. Their results collectively suggest that scavenging formaldehyde may be a useful treatment to limit motor dysfunction follow...

Full description

Bibliographic Details
Main Authors:	Dandan Yao, Qingyuan He, Shangyin Bai, Hang Zhao, Jun Yang, Dehua Cui, Yan Yu, Xuechao Fei, Yufei Mei, Ye Cheng, Shi Yan, Nayan Huang, Yalan Di, Xianjie Cai, Rui Wang, Yajuan Gao, Fangrao Cheng, Shengjie Zhao, Xu Yang, Xiang Cai, Hongbin Han, Jihui Lyu, Zhiqian Tong
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-08-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-021-02448-9

Similar Items

Author Correction: Accumulation of formaldehyde causes motor deficits in an in vivo model of hindlimb unloading
by: Dandan Yao, et al.
Published: (2021-10-01)

Calycosin prevents bone loss induced by hindlimb unloading
by: Xiang Jin, et al.
Published: (2022-07-01)

The Skeletal Cellular and Molecular Underpinning of the Murine Hindlimb Unloading Model
by: Priyanka Garg, et al.
Published: (2021-10-01)

Hindlimb unloading induces time-dependent disruption of testicular histology in mice
by: Asima Karim, et al.
Published: (2022-10-01)

Influence of Social Isolation During Prolonged Simulated Weightlessness by Hindlimb Unloading
by: Candice G. T. Tahimic, et al.
Published: (2019-09-01)

Beta-Catenin Haplo Insufficient Male Mice Do Not Lose Bone in Response to Hindlimb Unloading.
by: Delphine B Maurel, et al.
Published: (2016-01-01)

Effect of Microgravity on the Gut Microbiota Bacterial Composition in a Hindlimb Unloading Model
by: Ruqaiyyah Siddiqui, et al.
Published: (2022-11-01)

Insulin and exercise improved muscle function in rats with severe burns and hindlimb unloading
by: Juquan Song, et al.
Published: (2019-07-01)

Disruption of glucocorticoid signal in osteoblasts and osteocytes attenuates hindlimb unloading-induced bone loss in mice
by: Jiancheng Yang, et al.
Published: (2016-10-01)

Hydrogen Inhalation Ameliorates Oxidative Stress and Glucose Metabolism Disorder in the Brain of Hindlimb Unloading Rats
by: Xiaoyan Jin, et al.
Published: (2023-01-01)

Cordymin alleviates osteoporosis induced by hindlimb unloading via regulating the gut - microelements -bone axis --for non-clinical studies
by: Wei Qi, et al.
Published: (2023-12-01)

New Findings: Hindlimb Unloading Causes Nucleocytoplasmic Ca<sup>2+</sup> Overload and DNA Damage in Skeletal Muscle
by: Huajian Yang, et al.
Published: (2023-04-01)

The Combination of Soy Isoflavones and Resveratrol Preserve Bone Mineral Density in Hindlimb-Unloaded Mice
by: Yuko Tousen, et al.
Published: (2020-07-01)

ERK is involved in the reorganization of somatosensory cortical maps in adult rats submitted to hindlimb unloading.
by: Erwan Dupont, et al.
Published: (2011-03-01)

Age-dependent bone loss and recovery during hindlimb unloading and subsequent reloading in rats
by: Hailey C. Cunningham, et al.
Published: (2018-07-01)

Total Flavonoids of Drynariae Rhizoma Prevent Bone Loss Induced by Hindlimb Unloading in Rats
by: Shuanghong Song, et al.
Published: (2017-06-01)

Correction: Cordymin alleviates osteoporosis induced by hindlimb unloading via regulating the gut - microelements -bone axis --for non-clinical studies
by: Wei Qi, et al.
Published: (2024-01-01)

Myeloid cell infiltration in skeletal muscle after combined hindlimb unloading and radiation exposure in mice
by: Eric B. Emanuelsson, et al.
Published: (2023-06-01)

Impacts of radiation exposure, hindlimb unloading, and recovery on murine skeletal muscle cell telomere length
by: Elisia D. Tichy, et al.
Published: (2023-09-01)

Exercise Preconditioning Blunts Early Atrogenes Expression and Atrophy in Gastrocnemius Muscle of Hindlimb Unloaded Mice
by: Lorenza Brocca, et al.
Published: (2021-12-01)

αKlotho decreases after reduced weight-bearing from both spaceflight and hindlimb unloading
by: Jeffrey S. Willey, et al.
Published: (2022-06-01)

Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice
by: Amir Ali Khan, et al.
Published: (2022-07-01)

The effects of hindlimb unloading versus dietary cholesterol and resistance training on rat skeletal muscle responses
by: Teak V. Lee, et al.
Published: (2019-01-01)

Model of hindlimb unloading in adult female rats: Characterizing bone physicochemical, microstructural, and biomechanical properties.
by: Melise Jacon Peres-Ueno, et al.
Published: (2017-01-01)

Contribution of social isolation, restraint, and hindlimb unloading to changes in hemodynamic parameters and motion activity in rats.
by: Darya Tsvirkun, et al.
Published: (2012-01-01)

Bone mineral density of rat femurs after hindlimb unloading and different physical rehabilitation programs
by: Adelton Andrade Barbosa, et al.
Published: (2011-08-01)

Effects of Long-Term and Acute Hindlimb Unloading Model on Neuroelectrophysiological Signals of Hippocampal Interneurons and Pyramidal Cells Using Microelectrode Arrays
by: Hao Wang, et al.
Published: (2020-01-01)

Molecular and Metabolic Mechanism of Low-Intensity Pulsed Ultrasound Improving Muscle Atrophy in Hindlimb Unloading Rats
by: Lijun Sun, et al.
Published: (2021-11-01)

The Immunomodulatory Effect Of Radiofrequency Electromagnetic Field On Serum Cytokine Levels In A Mouse Model Of Hindlimb Unloading
by: Sima Aghajari, et al.
Published: (2021-01-01)

Cytoskeleton Structure in Mouse Sperm and Testes After 30 Days of Hindlimb Unloading and 12 Hours of Recovery
by: Maria A. Usik, et al.
Published: (2018-11-01)

Effects of photon irradiation in the presence and absence of hindlimb unloading on the behavioral performance and metabolic pathways in the plasma of Fischer rats
by: Jacob Raber, et al.
Published: (2024-01-01)

Functional Block of Interleukin-6 Reduces a Bone Pain Marker But Not Bone Loss in Hindlimb-Unloaded Mice
by: Hiroki Wakabayashi, et al.
Published: (2020-05-01)

HDAC4 Is Indispensable for Reduced Slow Myosin Expression at the Early Stage of Hindlimb Unloading in Rat Soleus Muscle
by: Inna I. Paramonova, et al.
Published: (2021-11-01)

Transcriptional responses of skeletal stem/progenitor cells to hindlimb unloading and recovery correlate with localized but not systemic multi-systems impacts
by: Cori N. Booker, et al.
Published: (2021-11-01)

The Impact of SRT2104 on Skeletal Muscle Mitochondrial Function, Redox Biology, and Loss of Muscle Mass in Hindlimb Unloaded Rats
by: Lauren T. Wesolowski, et al.
Published: (2023-07-01)

RNAseq and RNA molecular barcoding reveal differential gene expression in cortical bone following hindlimb unloading in female mice.
by: Jordan M Spatz, et al.
Published: (2021-01-01)

Serum multi-omics analysis in hindlimb unloading mice model: Insights into systemic molecular changes and potential diagnostic and therapeutic biomarkers
by: Zeinab Ibrahim, et al.
Published: (2024-01-01)

Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast‐twitch muscle in rats
by: Munehiro Uda, et al.
Published: (2024-03-01)

Stromal Lineage Precursors from Rodent Femur and Tibia Bone Marrows after Hindlimb Unloading: Functional Ex Vivo Analysis
by: Elena Markina, et al.
Published: (2023-05-01)

Effects of 5-Ion Beam Irradiation and Hindlimb Unloading on Metabolic Pathways in Plasma and Brain of Behaviorally Tested WAG/Rij Rats
by: Jacob Raber, et al.
Published: (2021-09-01)