Histopathological and Histochemical Study of Intestinal Cryptosporidiosis in Mice

This study was conducted to investigate the histopathological and histochemical alteration of intestinal mice infected with C. parvum isolated from calf feces. The result elucidate that histopathologcal changes represented by hypertrophy and hyperplasia of epithelium villi in mucosa and submucosal...

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Bibliographic Details
Main Authors: E. R. Al-Kennany, A. M. Rahawi, S. A. Al-Jabori
Format: Article
Language:English
Published: Faculty of Veterinary Medicine, University of Kufa 2012-12-01
Series:Kufa Journal for Veterinary Medical Sciences
Online Access:https://journal.uokufa.edu.iq/index.php/kjvs/article/view/3952
Description
Summary:This study was conducted to investigate the histopathological and histochemical alteration of intestinal mice infected with C. parvum isolated from calf feces. The result elucidate that histopathologcal changes represented by hypertrophy and hyperplasia of epithelium villi in mucosa and submucosal gland, presence of different developmental stages of parasite attached to brush border of epithelium and in crypt in addition to proliferation of mononuclear inflammatory cell and blunts of villi have been observed as compared with control group. Histochemcially, histological sections of infected mice revealed strong positive reaction with AB pH 1.0. In addition to positive reaction with PAS – AB pH 2.5 as compared with control group. Conclusion: This study investigated that infection with C. parvum cause changes in mucosubstances secreted from goblet cells of mucosal villi and submucosal glands.
ISSN:2077-9798
2959-8478