Early-life fluoxetine exposure reduced functional deficits after hypoxic–ischemia brain injury in rat pups

Early-life fluoxetine exposure reduced functional deficits after hypoxic–ischemia brain injury in rat pups

Neuroplasticity after perinatal programming may allow for neuroprotection against hypoxic–ischemia (HI) at birth. The cAMP response element-binding protein (CREB) is a key mediator of stimulus-induced nuclear responses that underlie survival, memory and plasticity of nervous system. Chronic treatmen...

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Bibliographic Details
Main Authors:	Ying-Chao Chang, Shun-Fen Tzeng, Lung Yu, A-Min Huang, Hsueh-Te Lee, Chao-Ching Huang, Chien-Jung Ho
Format:	Article
Language:	English
Published:	Elsevier 2006-10-01
Series:	Neurobiology of Disease
Subjects:	Fluoxetine cAMP response element-binding protein Brain-derived neurotrophic factor Neurogenesis Newborn Hypoxic–ischemia
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996106001392

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