Amantadine: an antiviral and antiparkinsonian agent
Amantadine is an antiviral agent that specifically inhibits influenza A virus replication at a micromolar concentration. This drug is also very effective in the treatment of human Parkinson's disease. Other important clinical applications of this agent have been studied recently, ranging from v...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2001-09-01
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| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-200109-0004_amantadine-an-antiviral-and-antiparkinsonian-agent.php |
| _version_ | 1797897840215719936 |
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| author | J. Staničová P. Miškovský V. Šutiak |
| author_facet | J. Staničová P. Miškovský V. Šutiak |
| author_sort | J. Staničová |
| collection | DOAJ |
| description | Amantadine is an antiviral agent that specifically inhibits influenza A virus replication at a micromolar concentration. This drug is also very effective in the treatment of human Parkinson's disease. Other important clinical applications of this agent have been studied recently, ranging from viral infections, e.g. herpes, herpes zoster neuralgia to granulomatosis and from neuroleptic extrapyramidal movement disease to depression and cocain dependence. Biological and pharmacological activities of amantadine presented in this paper are focused on the explanation of the mechanism of amantadine antiviral and antiparkinsonian effects and on general use of this agent in medicine. |
| first_indexed | 2024-04-10T08:03:38Z |
| format | Article |
| id | doaj.art-ff472373892144f987140e4e6a716ce2 |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T08:03:38Z |
| publishDate | 2001-09-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-ff472373892144f987140e4e6a716ce22023-02-23T03:48:54ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922001-09-01469-1024425610.17221/7884-VETMEDvet-200109-0004Amantadine: an antiviral and antiparkinsonian agentJ. Staničová0P. Miškovský1V. Šutiak2University of Veterinary Medicine, Košice, Slovak RepublicUniversity of Veterinary Medicine, Košice, Slovak RepublicUniversity of Veterinary Medicine, Košice, Slovak RepublicAmantadine is an antiviral agent that specifically inhibits influenza A virus replication at a micromolar concentration. This drug is also very effective in the treatment of human Parkinson's disease. Other important clinical applications of this agent have been studied recently, ranging from viral infections, e.g. herpes, herpes zoster neuralgia to granulomatosis and from neuroleptic extrapyramidal movement disease to depression and cocain dependence. Biological and pharmacological activities of amantadine presented in this paper are focused on the explanation of the mechanism of amantadine antiviral and antiparkinsonian effects and on general use of this agent in medicine.https://vetmed.agriculturejournals.cz/artkey/vet-200109-0004_amantadine-an-antiviral-and-antiparkinsonian-agent.phpinfluenza am2 proteinchemotherapychemoprophylaxisparkinson's disease |
| spellingShingle | J. Staničová P. Miškovský V. Šutiak Amantadine: an antiviral and antiparkinsonian agent Veterinární Medicína influenza a m2 protein chemotherapy chemoprophylaxis parkinson's disease |
| title | Amantadine: an antiviral and antiparkinsonian agent |
| title_full | Amantadine: an antiviral and antiparkinsonian agent |
| title_fullStr | Amantadine: an antiviral and antiparkinsonian agent |
| title_full_unstemmed | Amantadine: an antiviral and antiparkinsonian agent |
| title_short | Amantadine: an antiviral and antiparkinsonian agent |
| title_sort | amantadine an antiviral and antiparkinsonian agent |
| topic | influenza a m2 protein chemotherapy chemoprophylaxis parkinson's disease |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-200109-0004_amantadine-an-antiviral-and-antiparkinsonian-agent.php |
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