<b>Testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training</b> - doi: 10.4025/actascihealthsci.v35i2.16406
The mammalian testis is a complex organ with endocrine and exocrine functions. It consists of seminiferous tubules where the production of the male gametes called spermatogenesis occurs. This process is influenced by a number of factors including the use of physical performance-enhancing drugs. The...
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| Format: | Article |
| Language: | English |
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Universidade Estadual de Maringá
2013-06-01
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| Series: | Acta Scientiarum. Health Sciences |
| Subjects: | |
| Online Access: | http://186.233.154.254/ojs/index.php/ActaSciHealthSci/article/view/16406 |
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| author | Fernanda Ferrari Marcela de Paiva Foletto Solange Marta Franzói de Moraes Sidney Barnabé Peres Tânia Mara Segatelli Cecília Edna Mareze da Costa |
| author_facet | Fernanda Ferrari Marcela de Paiva Foletto Solange Marta Franzói de Moraes Sidney Barnabé Peres Tânia Mara Segatelli Cecília Edna Mareze da Costa |
| author_sort | Fernanda Ferrari |
| collection | DOAJ |
| description | The mammalian testis is a complex organ with endocrine and exocrine functions. It consists of seminiferous tubules where the production of the male gametes called spermatogenesis occurs. This process is influenced by a number of factors including the use of physical performance-enhancing drugs. The objective of this study was to evaluate the effects of the anabolic steroid nandrolone decanoate on the morphofunctional structure of testes in sedentary rats and rats subjected to moderate aerobic exercise training. Twenty-four male rats were divided into four experimental groups: sedentary control, sedentary treated, trained control and trained treated.The training lasted eight weeks and consisted of running on a programmable ergometer treadmill, tailored to train eight rats simultaneously. Treated animals received intramuscular injections of nandrolone decanoate (0.5 mg kg-1 body weight) during the last four weeks of physical training, while the control groups received intramuscular injections of vehicle (vegetable oil).The male reproductive system morphology showed that treatment with nandrolone decanoate, in both sedentary and trained rats, promoted morphological and functional changes that result in reduced efficiency of spermatogenesis. |
| first_indexed | 2024-12-20T00:01:58Z |
| format | Article |
| id | doaj.art-ff48863f41af4a83987cea032a4581c2 |
| institution | Directory Open Access Journal |
| issn | 1679-9291 1807-8648 |
| language | English |
| last_indexed | 2024-12-20T00:01:58Z |
| publishDate | 2013-06-01 |
| publisher | Universidade Estadual de Maringá |
| record_format | Article |
| series | Acta Scientiarum. Health Sciences |
| spelling | doaj.art-ff48863f41af4a83987cea032a4581c22022-12-21T20:00:48ZengUniversidade Estadual de MaringáActa Scientiarum. Health Sciences1679-92911807-86482013-06-0135216116710.4025/actascihealthsci.v35i2.1640610029<b>Testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training</b> - doi: 10.4025/actascihealthsci.v35i2.16406Fernanda Ferrari0Marcela de Paiva Foletto1Solange Marta Franzói de Moraes2Sidney Barnabé Peres3Tânia Mara Segatelli4Cecília Edna Mareze da Costa5Universidade Estadual de MaringáUniversidade Estadual de MaringáUniversidade Estadual de MaringáUniversidade Estadual de MaringáUniversidade Federal de Minas GeraisUniversidade Estadual de MaringáThe mammalian testis is a complex organ with endocrine and exocrine functions. It consists of seminiferous tubules where the production of the male gametes called spermatogenesis occurs. This process is influenced by a number of factors including the use of physical performance-enhancing drugs. The objective of this study was to evaluate the effects of the anabolic steroid nandrolone decanoate on the morphofunctional structure of testes in sedentary rats and rats subjected to moderate aerobic exercise training. Twenty-four male rats were divided into four experimental groups: sedentary control, sedentary treated, trained control and trained treated.The training lasted eight weeks and consisted of running on a programmable ergometer treadmill, tailored to train eight rats simultaneously. Treated animals received intramuscular injections of nandrolone decanoate (0.5 mg kg-1 body weight) during the last four weeks of physical training, while the control groups received intramuscular injections of vehicle (vegetable oil).The male reproductive system morphology showed that treatment with nandrolone decanoate, in both sedentary and trained rats, promoted morphological and functional changes that result in reduced efficiency of spermatogenesis.http://186.233.154.254/ojs/index.php/ActaSciHealthSci/article/view/16406anabolic agenttestisspermatogenesisnandrolone decanoate |
| spellingShingle | Fernanda Ferrari Marcela de Paiva Foletto Solange Marta Franzói de Moraes Sidney Barnabé Peres Tânia Mara Segatelli Cecília Edna Mareze da Costa <b>Testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training</b> - doi: 10.4025/actascihealthsci.v35i2.16406 Acta Scientiarum. Health Sciences anabolic agent testis spermatogenesis nandrolone decanoate |
| title | <b>Testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training</b> - doi: 10.4025/actascihealthsci.v35i2.16406 |
| title_full | <b>Testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training</b> - doi: 10.4025/actascihealthsci.v35i2.16406 |
| title_fullStr | <b>Testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training</b> - doi: 10.4025/actascihealthsci.v35i2.16406 |
| title_full_unstemmed | <b>Testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training</b> - doi: 10.4025/actascihealthsci.v35i2.16406 |
| title_short | <b>Testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training</b> - doi: 10.4025/actascihealthsci.v35i2.16406 |
| title_sort | b testis morphophysiology of rats treated with nandrolone decanoate and submitted to physical training b doi 10 4025 actascihealthsci v35i2 16406 |
| topic | anabolic agent testis spermatogenesis nandrolone decanoate |
| url | http://186.233.154.254/ojs/index.php/ActaSciHealthSci/article/view/16406 |
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