Efficacy and Safety of Clonidine in the Treatment of Acute Mania in Bipolar Disorder: A Systematic Review

Efficacy and Safety of Clonidine in the Treatment of Acute Mania in Bipolar Disorder: A Systematic Review

Clonidine, an alpha-2 adrenergic agonist, has been proposed as an antimanic agent that acts by reducing noradrenergic transmission. We conducted a systematic review to examine the efficacy and safety of clonidine for acute mania/hypomania. A comprehensive literature search was performed to identify...

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Bibliographic Details
Main Authors: Prakamya Singal, Nicolas A. Nuñez, Boney Joseph, Leslie C. Hassett, Ashok Seshadri, Balwinder Singh
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Brain Sciences
Subjects:
clonidine
systematic review
acute mania
bipolar disorder
Online Access:https://www.mdpi.com/2076-3425/13/4/547

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