Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?

Short or Long Interval between Priming and Boosting: Does It Impact on the Vaccine Immunogenicity?

Characterizing the impact of the vaccination schedule on the induction of B and T cell immune responses is critical for improving vaccine immunogenicity. Here we compare the effect of a short (4 weeks) or a long (18 weeks) interval between priming and boosting in mice, using a model vaccine formulat...

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Bibliographic Details
Main Authors: Elena Pettini, Gabiria Pastore, Fabio Fiorino, Donata Medaglini, Annalisa Ciabattini
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Vaccines
Subjects:
immunization
alum
B cell response
T cell response
antibodies
prime–boost schedules
Online Access:https://www.mdpi.com/2076-393X/9/3/289

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