Inflammatory Response Following Peripheral Endovascular Treatment Correlates with the Extent of Periprocedural Arterial Injury
The aim was to examine whether the postprocedural change in C-reactive protein (CRP) and fibrinogen levels was associated with the extent of periprocedural arterial injury caused by endovascular treatment (EVT). The study recruited 71 patients undergoing EVT. Eighty-four patients that underwent angi...
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| Format: | Article |
| Language: | English |
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Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2018-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/317892 |
| _version_ | 1797207518850580480 |
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| author | Tajana Turk Otmar Rubin Gordan Šarić Tonći Mišević Vjekoslav Kopačin Damir Kovač Vedran Ivković Vedran Farkaš Vatroslav Šerić |
| author_facet | Tajana Turk Otmar Rubin Gordan Šarić Tonći Mišević Vjekoslav Kopačin Damir Kovač Vedran Ivković Vedran Farkaš Vatroslav Šerić |
| author_sort | Tajana Turk |
| collection | DOAJ |
| description | The aim was to examine whether the postprocedural change in C-reactive protein (CRP) and fibrinogen levels was associated with the extent of periprocedural arterial injury caused by endovascular treatment (EVT). The study recruited 71 patients undergoing EVT. Eighty-four patients that underwent angiography served as a control group. CRP and fibrinogen were measured at baseline, and at 8, 24 and 48 hours following the procedure. In all experimental group patients, lesion complexity, percutaneous transluminal angioplasty (PTA) treated segment length, balloon inflation time and stented segment length were recorded. There was significant increase in plasma CRP and fibrinogen levels 48 hours following EVT (p<0.001). There was no significant difference in CRP and fibrinogen levels among different TASC groups. CRP levels were significantly higher in stent subgroup compared to PTA subgroup. Significant positive correlation was found between PTA treated segment length and CRP increase between 8 and 24 hours following EVT (r=0.313, p=0.02), balloon inflation time and CRP increase in the aforementioned time frame (r=0.270, p=0.03), as well as between CRP increase at 8 hours and stented segment length (r=0.535, p=0.01). This study showed that the arterial injury caused by EVT reflected on the level of inflammatory biomarkers. |
| first_indexed | 2024-04-24T09:24:11Z |
| format | Article |
| id | doaj.art-ff59dd6a75f94f36bc651aecfa7318fc |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:24:11Z |
| publishDate | 2018-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-ff59dd6a75f94f36bc651aecfa7318fc2024-04-15T15:23:06ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512018-01-0157.4.63063710.20471/acc.2018.57.04.04Inflammatory Response Following Peripheral Endovascular Treatment Correlates with the Extent of Periprocedural Arterial InjuryTajana Turk0Otmar Rubin1Gordan Šarić2Tonći Mišević3Vjekoslav Kopačin4Damir Kovač5Vedran Ivković6Vedran Farkaš7Vatroslav Šerić8Department of Diagnostic and Interventional Radiology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaDepartment of Diagnostic and Interventional Radiology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaDepartment of Surgery, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaDepartment of Surgery, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaDepartment of Surgery, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaDepartment of Chemistry, Biochemistry and Clinical Chemistry, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, CroatiaThe aim was to examine whether the postprocedural change in C-reactive protein (CRP) and fibrinogen levels was associated with the extent of periprocedural arterial injury caused by endovascular treatment (EVT). The study recruited 71 patients undergoing EVT. Eighty-four patients that underwent angiography served as a control group. CRP and fibrinogen were measured at baseline, and at 8, 24 and 48 hours following the procedure. In all experimental group patients, lesion complexity, percutaneous transluminal angioplasty (PTA) treated segment length, balloon inflation time and stented segment length were recorded. There was significant increase in plasma CRP and fibrinogen levels 48 hours following EVT (p<0.001). There was no significant difference in CRP and fibrinogen levels among different TASC groups. CRP levels were significantly higher in stent subgroup compared to PTA subgroup. Significant positive correlation was found between PTA treated segment length and CRP increase between 8 and 24 hours following EVT (r=0.313, p=0.02), balloon inflation time and CRP increase in the aforementioned time frame (r=0.270, p=0.03), as well as between CRP increase at 8 hours and stented segment length (r=0.535, p=0.01). This study showed that the arterial injury caused by EVT reflected on the level of inflammatory biomarkers.https://hrcak.srce.hr/file/317892C-reactive proteinFibrinogenStentsAngiographyEndovascular proceduresAngioplasty |
| spellingShingle | Tajana Turk Otmar Rubin Gordan Šarić Tonći Mišević Vjekoslav Kopačin Damir Kovač Vedran Ivković Vedran Farkaš Vatroslav Šerić Inflammatory Response Following Peripheral Endovascular Treatment Correlates with the Extent of Periprocedural Arterial Injury Acta Clinica Croatica C-reactive protein Fibrinogen Stents Angiography Endovascular procedures Angioplasty |
| title | Inflammatory Response Following Peripheral Endovascular Treatment Correlates with the Extent of Periprocedural Arterial Injury |
| title_full | Inflammatory Response Following Peripheral Endovascular Treatment Correlates with the Extent of Periprocedural Arterial Injury |
| title_fullStr | Inflammatory Response Following Peripheral Endovascular Treatment Correlates with the Extent of Periprocedural Arterial Injury |
| title_full_unstemmed | Inflammatory Response Following Peripheral Endovascular Treatment Correlates with the Extent of Periprocedural Arterial Injury |
| title_short | Inflammatory Response Following Peripheral Endovascular Treatment Correlates with the Extent of Periprocedural Arterial Injury |
| title_sort | inflammatory response following peripheral endovascular treatment correlates with the extent of periprocedural arterial injury |
| topic | C-reactive protein Fibrinogen Stents Angiography Endovascular procedures Angioplasty |
| url | https://hrcak.srce.hr/file/317892 |
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