Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience
Abstract Background Chronic kidney disease stage 5 (CKD 5) populations have peculiar risk for severe Covid-19 infection. Moreover; pediatric data are sparse and lacking. The aim of this study is to report our experience in CKD 5 children treated by hemodialysis (CKD 5D) and CKD 5 children after kidn...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-08-01
|
| Series: | Italian Journal of Pediatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13052-022-01345-z |
| _version_ | 1811340391397457920 |
|---|---|
| author | Fatina I. Fadel Samar Sabry Mohamed A. Abdel Mawla Rasha Essam Eldin Galal Doaa M. Salah Rasha Helmy Yasmen Ramadan Wessam Elzayat May Abdelfattah Eman Abobakr Abd Alazem |
| author_facet | Fatina I. Fadel Samar Sabry Mohamed A. Abdel Mawla Rasha Essam Eldin Galal Doaa M. Salah Rasha Helmy Yasmen Ramadan Wessam Elzayat May Abdelfattah Eman Abobakr Abd Alazem |
| author_sort | Fatina I. Fadel |
| collection | DOAJ |
| description | Abstract Background Chronic kidney disease stage 5 (CKD 5) populations have peculiar risk for severe Covid-19 infection. Moreover; pediatric data are sparse and lacking. The aim of this study is to report our experience in CKD 5 children treated by hemodialysis (CKD 5D) and CKD 5 children after kidney transplantation (KTR) during one year of Covid-19 pandemic. Methods Retrospective analysis of 57 CKD 5 children with Covid-19 like symptoms during 1 year pandemic was performed. A cohort of 19 confirmed patients (13 CKD 5D and 6 KTR) was analyzed in details as regard clinical, laboratory, radiological criteria, management and their short term outcome. Results Conclusion Pediatric patients on regular HD (CKD 5D) are at higher risk and worse outcome of Covid-19 infection than KT recipients (KTR). Pre-existing HTN and shorter duration after KT are potential risk factors. Reversible AGD after KT and CVC related infections in HD patients are additional presenting features of Covid-19 infection. |
| first_indexed | 2024-04-13T18:40:21Z |
| format | Article |
| id | doaj.art-ff5e2dcd35cf4313a4223bd6273a2e4b |
| institution | Directory Open Access Journal |
| issn | 1824-7288 |
| language | English |
| last_indexed | 2024-04-13T18:40:21Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Italian Journal of Pediatrics |
| spelling | doaj.art-ff5e2dcd35cf4313a4223bd6273a2e4b2022-12-22T02:34:44ZengBMCItalian Journal of Pediatrics1824-72882022-08-014811910.1186/s13052-022-01345-zCovid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experienceFatina I. Fadel0Samar Sabry1Mohamed A. Abdel Mawla2Rasha Essam Eldin Galal3Doaa M. Salah4Rasha Helmy5Yasmen Ramadan6Wessam Elzayat7May Abdelfattah8Eman Abobakr Abd Alazem9Department of Pediatrics, Pediatric Nephrology and Transplantation Units, Kasr Alainy Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, Pediatric Nephrology and Transplantation Units, Kasr Alainy Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, National Research CenterDepartment of Pediatrics, Pediatric Nephrology and Transplantation Units, Kasr Alainy Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, Pediatric Nephrology and Transplantation Units, Kasr Alainy Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, Pediatric Nephrology and Transplantation Units, Kasr Alainy Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, Pediatric Nephrology and Transplantation Units, Kasr Alainy Faculty of Medicine, Cairo UniversityDepartment of Radiodiagnosis, Kasr Alainy Faculty of Medicine, Cairo UniversityDepartment of Clinical Pathology, Faculty of Medicine, Cairo UniversityDepartment of Pediatrics, Pediatric Nephrology and Transplantation Units, Kasr Alainy Faculty of Medicine, Cairo UniversityAbstract Background Chronic kidney disease stage 5 (CKD 5) populations have peculiar risk for severe Covid-19 infection. Moreover; pediatric data are sparse and lacking. The aim of this study is to report our experience in CKD 5 children treated by hemodialysis (CKD 5D) and CKD 5 children after kidney transplantation (KTR) during one year of Covid-19 pandemic. Methods Retrospective analysis of 57 CKD 5 children with Covid-19 like symptoms during 1 year pandemic was performed. A cohort of 19 confirmed patients (13 CKD 5D and 6 KTR) was analyzed in details as regard clinical, laboratory, radiological criteria, management and their short term outcome. Results Conclusion Pediatric patients on regular HD (CKD 5D) are at higher risk and worse outcome of Covid-19 infection than KT recipients (KTR). Pre-existing HTN and shorter duration after KT are potential risk factors. Reversible AGD after KT and CVC related infections in HD patients are additional presenting features of Covid-19 infection.https://doi.org/10.1186/s13052-022-01345-zCovid-19, Hemodialysis, Hypertension, Kidney Transplantation |
| spellingShingle | Fatina I. Fadel Samar Sabry Mohamed A. Abdel Mawla Rasha Essam Eldin Galal Doaa M. Salah Rasha Helmy Yasmen Ramadan Wessam Elzayat May Abdelfattah Eman Abobakr Abd Alazem Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience Italian Journal of Pediatrics Covid-19, Hemodialysis, Hypertension, Kidney Transplantation |
| title | Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience |
| title_full | Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience |
| title_fullStr | Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience |
| title_full_unstemmed | Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience |
| title_short | Covid-19 in Egyptian hemodialysis and kidney transplant children: retrospective analysis of single center experience |
| title_sort | covid 19 in egyptian hemodialysis and kidney transplant children retrospective analysis of single center experience |
| topic | Covid-19, Hemodialysis, Hypertension, Kidney Transplantation |
| url | https://doi.org/10.1186/s13052-022-01345-z |
| work_keys_str_mv | AT fatinaifadel covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT samarsabry covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT mohamedaabdelmawla covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT rashaessameldingalal covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT doaamsalah covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT rashahelmy covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT yasmenramadan covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT wessamelzayat covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT mayabdelfattah covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience AT emanabobakrabdalazem covid19inegyptianhemodialysisandkidneytransplantchildrenretrospectiveanalysisofsinglecenterexperience |