Conservation and diversity of the eukaryotic SAGA coactivator complex across kingdoms

Conservation and diversity of the eukaryotic SAGA coactivator complex across kingdoms

Abstract The SAGA complex is an evolutionarily conserved transcriptional coactivator that regulates gene expression through its histone acetyltransferase and deubiquitylase activities, recognition of specific histone modifications, and interactions with transcription factors. Multiple lines of evide...

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Bibliographic Details
Main Authors: Ying-Jiun C. Chen, Sharon Y. R. Dent
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Epigenetics & Chromatin
Subjects:
SAGA complex
Transcription
Coactivator
Epigenetics
GCN5
Development
Online Access:https://doi.org/10.1186/s13072-021-00402-x

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