Binding polymorphism in the DNA bound state of the Pdx1 homeodomain.

Binding polymorphism in the DNA bound state of the Pdx1 homeodomain.

The subtle effects of DNA-protein recognition are illustrated in the homeodomain fold. This is one of several small DNA binding motifs that, in spite of limited DNA binding specificity, adopts crucial, specific roles when incorporated in a transcription factor. The homeodomain is composed of a 3-hel...

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Bibliographic Details
Main Authors: Volodymyr Babin, Dongli Wang, Robert B Rose, Celeste Sagui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3738460?pdf=render

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