Genetic interaction effects reveal lipid-metabolic and inflammatory pathways underlying common metabolic disease risks

Genetic interaction effects reveal lipid-metabolic and inflammatory pathways underlying common metabolic disease risks

Abstract Background Common metabolic diseases, including type 2 diabetes, coronary artery disease, and hypertension, arise from disruptions of the body’s metabolic homeostasis, with relatively strong contributions from genetic risk factors and substantial comorbidity with obesity. Although genome-wi...

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Bibliographic Details
Main Authors: Hyung Jun Woo, Jaques Reifman
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Medical Genomics
Subjects:
Metabolic syndrome
Type 2 diabetes
Coronary artery disease
Hypertension
Epistasis
Genome-wide association studies
Online Access:http://link.springer.com/article/10.1186/s12920-018-0373-7

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http://link.springer.com/article/10.1186/s12920-018-0373-7

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