Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway

Artemisinin Confers Neuroprotection against 6-OHDA-Induced Neuronal Injury In Vitro and In Vivo through Activation of the ERK1/2 Pathway

Parkinson’s disease (PD) is an age-related, progressive neurodegenerative disease characterized by the gradual and massive loss of dopaminergic neurons in the substantia nigra pars compacta (SNc). We have recently reported that artemisinin, an FDA-approved first-line antimalarial drug, possesses a n...

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Bibliographic Details
Main Authors: Qin Li, Shuai Li, Jiankang Fang, Chao Yang, Xia Zhao, Qing Wang, Wenshu Zhou, Wenhua Zheng
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Molecules
Subjects:
artemisinin
6-OHDA
MPTP/MPP<sup>+</sup>
apoptosis
Parkinson’s disease
Online Access:https://www.mdpi.com/1420-3049/28/14/5527

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