scDemultiplex: An iterative beta-binomial model-based method for accurate demultiplexing with hashtag oligos
Single-cell sequencing have been widely used to characterize cellular heterogeneity. Sample multiplexing where multiple samples are pooled together for single-cell experiments, attracts wide attention due to its benefits of increasing capacity, reducing costs, and minimizing batch effects. To analyz...
Main Authors: | Li-Ching Huang, Lindsey K. Stolze, Hua-Chang Chen, Alexander Gelbard, Yu Shyr, Qi Liu, Quanhu Sheng |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S200103702300288X |
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