New alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition: a metabolomics appraisal
Abstract The formulation of sustainable fish feeds based on plant ingredients supplemented by alternative ingredients to plant (insect, micro-algae, yeast) and genetic selection of fish for plant-based diets were tested on rainbow trout in two separate experiments. Plant-based diets and correspondin...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-11-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-46809-2 |
| _version_ | 1797630281079848960 |
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| author | Simon Roques Catherine Deborde Sandrine Skiba-Cassy Françoise Médale Mathilde Dupont-Nivet Florence Lefevre Jérome Bugeon Laurent Labbé Yann Marchand Annick Moing Benoit Fauconneau |
| author_facet | Simon Roques Catherine Deborde Sandrine Skiba-Cassy Françoise Médale Mathilde Dupont-Nivet Florence Lefevre Jérome Bugeon Laurent Labbé Yann Marchand Annick Moing Benoit Fauconneau |
| author_sort | Simon Roques |
| collection | DOAJ |
| description | Abstract The formulation of sustainable fish feeds based on plant ingredients supplemented by alternative ingredients to plant (insect, micro-algae, yeast) and genetic selection of fish for plant-based diets were tested on rainbow trout in two separate experiments. Plant-based diets and corresponding diets supplemented with an ingredient mix: insect, micro-algae and yeast in Experiment A, and insect and yeast in Experiment B were compared to commercial-like diets. In experiment A, the mix-supplemented diet was successful in compensating the altered growth performance of fish fed their respective plant-based diet compared to those fed the commercial diet, by restoring feed conversion. In experiment B, the selected line demonstrated improved growth performances of fish fed mix-supplemented and plant-based diets compared to the non-selected line. Metabolomics demonstrated a plasma compositional stability in fish fed mix-supplemented and basal plant-based diets comprising an amino acid accumulation and a glucose depletion, compared to those fed commercial diets. The selected line fed mix-supplemented and commercial diets showed changes in inositol, ethanol and methanol compared to the non-selected line, suggesting an involvement of microbiota. Changes in plasma glycine-betaine content in fish fed the mix-supplemented diet suggest the ability of the selected line to adapt to alternative ingredients. |
| first_indexed | 2024-03-11T11:04:58Z |
| format | Article |
| id | doaj.art-ff69b84c726645c1b81f4b5b5928a6c7 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-11T11:04:58Z |
| publishDate | 2023-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-ff69b84c726645c1b81f4b5b5928a6c72023-11-12T12:17:07ZengNature PortfolioScientific Reports2045-23222023-11-0113111610.1038/s41598-023-46809-2New alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition: a metabolomics appraisalSimon Roques0Catherine Deborde1Sandrine Skiba-Cassy2Françoise Médale3Mathilde Dupont-Nivet4Florence Lefevre5Jérome Bugeon6Laurent Labbé7Yann Marchand8Annick Moing9Benoit Fauconneau10INRAE, Univ. Pau & Pays Adour, E2S UPPA, Nutrition, Métabolisme et Aquaculture, UMR 1419Bordeaux Metabolome, MetaboHUB, Centre INRAE de Nouvelle-Aquitaine BordeauxINRAE, Univ. Pau & Pays Adour, E2S UPPA, Nutrition, Métabolisme et Aquaculture, UMR 1419INRAE, Univ. Pau & Pays Adour, E2S UPPA, Nutrition, Métabolisme et Aquaculture, UMR 1419Université Paris-Saclay, INRAE, AgroParisTech, Génétique Animale et Biologie Intégrative, UMR 1313INRAE, Laboratoire de Physiologie et Génomique des Poissons, UR 1037INRAE, Laboratoire de Physiologie et Génomique des Poissons, UR 1037INRAE, UE0937, PEIMALe GouessantBordeaux Metabolome, MetaboHUB, Centre INRAE de Nouvelle-Aquitaine BordeauxINRAE, Univ. Pau & Pays Adour, E2S UPPA, Nutrition, Métabolisme et Aquaculture, UMR 1419Abstract The formulation of sustainable fish feeds based on plant ingredients supplemented by alternative ingredients to plant (insect, micro-algae, yeast) and genetic selection of fish for plant-based diets were tested on rainbow trout in two separate experiments. Plant-based diets and corresponding diets supplemented with an ingredient mix: insect, micro-algae and yeast in Experiment A, and insect and yeast in Experiment B were compared to commercial-like diets. In experiment A, the mix-supplemented diet was successful in compensating the altered growth performance of fish fed their respective plant-based diet compared to those fed the commercial diet, by restoring feed conversion. In experiment B, the selected line demonstrated improved growth performances of fish fed mix-supplemented and plant-based diets compared to the non-selected line. Metabolomics demonstrated a plasma compositional stability in fish fed mix-supplemented and basal plant-based diets comprising an amino acid accumulation and a glucose depletion, compared to those fed commercial diets. The selected line fed mix-supplemented and commercial diets showed changes in inositol, ethanol and methanol compared to the non-selected line, suggesting an involvement of microbiota. Changes in plasma glycine-betaine content in fish fed the mix-supplemented diet suggest the ability of the selected line to adapt to alternative ingredients.https://doi.org/10.1038/s41598-023-46809-2 |
| spellingShingle | Simon Roques Catherine Deborde Sandrine Skiba-Cassy Françoise Médale Mathilde Dupont-Nivet Florence Lefevre Jérome Bugeon Laurent Labbé Yann Marchand Annick Moing Benoit Fauconneau New alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition: a metabolomics appraisal Scientific Reports |
| title | New alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition: a metabolomics appraisal |
| title_full | New alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition: a metabolomics appraisal |
| title_fullStr | New alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition: a metabolomics appraisal |
| title_full_unstemmed | New alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition: a metabolomics appraisal |
| title_short | New alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition: a metabolomics appraisal |
| title_sort | new alternative ingredients and genetic selection are the next game changers in rainbow trout nutrition a metabolomics appraisal |
| url | https://doi.org/10.1038/s41598-023-46809-2 |
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